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Ras and Other GTPases in Cancer: From Basic to Applied Research

Abstract: In the current Research Topic (RT), we provide insights on the small GTPase biology, from protein synthesis to disease, by presenting a Research Topic of original and review articles describing distinct GTPases, with special attention to RAS proteins. The RAS superfamily comprises a large family of small GTPases, where the members of the RAS, RHO, and RAB families are the most well-characterized. These small proteins cycle between a GDP-bound inactive and a GTP-bound active state, thus mediating several cellular processes such as intracellular trafficking, cytoskeletal organization, cell migration, proliferation, differentiation, and gene expression.

 Fuente: Front. Mol. Biosci. 8:804818

 Editorial: Frontiers Media

 Fecha de publicación: 29/11/2021

 Nº de páginas: 2

 Tipo de publicación: Artículo de Revista

 DOI: 10.3389/fmolb.2021.804818

 ISSN: 2296-889X

 Url de la publicación: https://www.frontiersin.org/articles/10.3389/fmolb.2021.804818/full

Autoría

KWANG-JIN, CHO

JIN, RUI LIANG

ARAN, VERONICA