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Consumption of aspartame and other artificial sweeteners and risk of cancer in the Spanish multicase-control study (MCC-Spain)

Abstract: Use of artificial sweeteners (AS) such as aspartame, cyclamate, saccharin and sucralose is widespread. We evaluated the association of use of aspartame and other AS with cancer. In total 1881 colorectal, 1510 breast, 972 prostate and 351 stomach cancer and 109 chronic lymphocytic leukaemia (CLL) cases and 3629 population controls from the Spanish Multicase-Control (MCC-Spain) study were recruited (2008-2013). The consumption of AS, from table-top sweeteners and artificially sweetened beverages, was assessed through a self-administered and validated food frequency questionnaire (FFQ). Sex-specific quartiles among controls were determined to compare moderate consumers (

 Autoría: Palomar-Cros A., Straif K., Romaguera D., Aragonés N., Castaño-Vinyals G., Martin V., Moreno V., Gómez-Acebo I., Guevara M., Aizpurua A., Molina-Barceló A., Jiménez-Moleón J.J., Tardón A., Contreras-Llanes M., Marcos-Gragera R., Huerta J.M., Pérez-Gómez B., Espinosa A., Hernández-Segura N., Obón-Santacana M., Alonso-Molero J., Burgui R., Amiano P., Pinto-Carbó M., Olmedo-Requena R., Fernández-Tardón G., Santos-Sánchez V., Fernández de Larrea-

 Fuente: International Journal of Cancer, 2023, 153, 979-993

 Editorial: Wiley-Liss

 Año de publicación: 2023

 Nº de páginas: 16

 Tipo de publicación: Artículo de Revista

 DOI: 10.1002/ijc.34577

 ISSN: 0020-7136,1097-0215

 Proyecto español: RD12/0036/0036

 Url de la publicación: https://doi.org/10.1002/ijc.34577

Autoría

PALOMAR-CROS, ANNA

STRAIF, KURT

ROMAGUERA, DORA

ARAGONÉS, NURIA

CASTAÑO-VINYALS, GEMMA

MARTÍN, VICENTE

MORENO, VÍCTOR

GUEVARA, MARCELA

AIZPURUA, AMAIA

MOLINA-BARCELÓ, ANA

JIMÉNEZ-MOLEÓN, JOSÉ-JUAN

TARDÓN, ADONINA

CONTRERAS-LLANES, MANUEL

MARCOS-GRAGERA, RAFAEL

HUERTA, JOSÉ M.

PÉREZ-GÓMEZ, BEATRIZ