Alfonso is Gradutated with Excellence in Biochemistry and Molecular Biology by Universidad del Pais Vasco (2017). During his Bachelor studies, he collaborated with Patricia Aspichueta's lab and Juan Iriberri's lab, where he performed his Bachelor Final Thesis.
He obtained an MSc in Evolutionary Genetics and Genomics from Universidad de Barcelona (2018). Under the supervision of Iñaki Ruiz-Trillo and Andrej Ondracka, in the Multi-Cell Genome Lab, he performed his Master Thesis on the genomic changes that led to the appearance of the multicellularity in animals.
In March 2019, he joined the Intergenomics group in the IBBTEC. Under the supervision of Fernando de la Cruz and Raúl Fernández he embarked on the adventure of characterizing an experimentally evolved strain of Synechococcus elongatusPCC7942, with the purpose of obtaining a fast-growing platform of high-value biotechnological compounds, and hopefully, write this PhD thesis.
Intergenomics
Research lines
– Evolution and Ecology:
• Classification of conjugative and mobilizable plasmids based on their relaxase sequences.
• Conjugative systems of Cyanobacteria and Actinomycetes.
– Molecular Engines: Protein and DNA transporters across bacterial membranes
– Protein Engineering: Conjugative relaxases as a target for the inhibition of the dissemination of antibiotic resistance.
– Systems Biology
Funding
- Nuevas estrategias para el control de infecciones nosocomiales. INNOECO RTC-2015-3184-1.
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“Promover el desarrollo tecnológico, la innovación y una investigación de calidad” |
- Plásmidos ortogonales para Biología Sintética y de Sistemas. Ministerio de Educación (BFU2011-26608).
- Bacterial Computing with Engineered Populations (BACTOCOM). European Union 7th Framework. Programme, Area Information and Communication Technologies (FP7-ICT-2009-4; Proyecto nº 248919).
- EVOTAR: Evolution and transfer of antibiotic resistance (Project no. 282004). European Union FP7-HEALTH 2011.2.3.1-2.
- Diversidad y distribución de plásmidos de bacterias ácido-lácticas. Acción Integrada Hispano-Serbia. PRI-AIBSE-2011-1186. IP: Fernando de la Cruz
- INGENIERÍA GENÉTICA DE ESCHERICHIA COLI PARA MEJORAR LA PRODUCCIÓN DE LÍPIDOS RICOS EN ÁCIDOS GRASOS OMEGA-3 (TF16-XX-003), cofinanciado por SODERCAN S.A. y el Programa Operativo FEDER
