Inglés (Estados Unidos)

ibbtec@unican.es

Félix Sangari García (IP)

IBBTEC. c/ Albert Einstein, 22; 39011 Santander
felix.sangari@unican.es
942 202229
Molecular Biology of Brucella Pathogenicity
Principal Investigator
Microbiology & Genomics
Department of Microbiology & Genomics

Molecular Biology of Brucella Pathogenicity

Research lines

Brucella virulence factors (and their regulation).
Metagenomics and microbial ecology

Group history

Our research group holds a long record of activity in the field of Molecular Microbiology. Our previous work in mechanisms of recombination and mobility of antibiotic resistance genes in medically important bacteria was followed by the analysis of molecular pathogenicity of Brucella giving significant contributions to new vaccines and epidemiological methods. By adopting high throughput methods and new generation sequencing we broadened our studies in Brucella and starting moving to the field of metagenomics and ambiental microbiology.

Funding

Control y seguimiento del biodeterioro y de las condiciones ambientales del agua de infiltracion y de las emisiones de gas radón de la cueva de Altamira" Ref.: 2018CC100242. Ministerio de Cultura y Deprte. Subdirección General de Museos Estatales. Duración 15/10/2018-01/09/2020.

Citizen Science to Raise Antimicrobial Resistance Awareness in the Community: The MicroMundo Project in Spain and Portugal.

Gil-Serna J, Sangari F, et al.

Microb Biotechnol. 2025 Mar;18(3):e70123

Effects of vaccination with Brucella melitensis, strains Rev 1 ΔeryCD and Rev 1, on the reproductive system of young male goats

López Vásquez IA, (…) Sangari F et al.

Rev Argent Microbiol. 2024 Mar 6:S0325-7541(24)00005-1. Online ahead of print.

The microbiome of the ice-capped Cayambe Volcanic Complex in Ecuador

Díaz M, Monfort-Lanzas P, Quiroz-Moreno C, Rivadeneira E, Castillejo P, Arnau V, Díaz W, Agathos SN, Sangari FJ, Jarrín-V P, Molina CA

Front Microbiol. 2023 May 5;14:1154815.

Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase

Alvarez-Dominguez C, Salcines-Cuevas D, Teran-Navarro H, Calderon-Gonzalez R, Tobes R, Garcia I, Grijalvo S, Paradela A, Seoane A, Sangari FJ, Fresno M, Calvo-Montes J, Pérez Del Molino Bernal IC, Yañez-Diaz S.

Front Cell Infect Microbiol. 2020 Oct 28;10:573348. doi: 10.3389/fcimb.2020.573348. eCollection 2020.

#EUROmicroMOOC: using Twitter to share trends in Microbiology worldwide

López-Goñi I, Giner-Lamia J, Álvarez-Ordoñez A, Benitez-Páez A, Claessen D, Cortesao M, de Toro M, García-Ruano D, Granato ET, Kovács ÁT, Romalde JL, Sana TG, Sánchez-Angulo M, Sangari FJ, Smits WK, Sturm T, Thomassin JL, Valdehuesa KNG, Zapotoczna M.

FEMS Microbiol Lett. 2019 Jun 1;366(11):fnz141.

Polymorphisms in Brucella Carbonic anhydrase II mediate CO2 dependence and fitness in vivo.

García Lobo JM, Ortiz Y, González-Riancho C, Seoane A, Arellano-Reynoso B, and Sangari FJ.

Frontiers in Microbiology, 2019 (BioRxiv doi: 10.1101/804740)

Twitter as a Tool for Teaching and Communicating Microbiology: The #microMOOCSEM Initiative.

López-Goñi I, et al. Twitter as a Tool for Teaching and Communicating Microbiology: The #microMOOCSEM Initiative. J Microbiol Biol Educ. 2016 Dec 2;17(3):492-494. doi: 10.1128/jmbe.v17i3.1200

J Microbiol Biol Educ. 2016 Dec 2;17(3):492-494. doi: 10.1128/jmbe.v17i3.1200

The exploration of Brucella transcriptome: From the ORFeome to RNAseq (book).

García-Lobo JM Rodríguez MC,Seoane A, Sangari FJ, López-Goñi I. Lopez Goñi and O'Callaghan eds. Brucella. Molecular Microbiology and Genomics. pp 89-102. Caister Academic Press. Norfolk, UK, 2012.

[pubmed]

Evaluation of the effects of erythritol on gene expression in Brucella abortus.

Rodríguez MC, Viadas C, Seoane A, Sangari FJ, López-Goñi I, García-Lobo JM. PLoS One. 2012;7(12):e50876. doi: 10.1371/journal.pone.0050876.

[pubmed]

Transfer of R388 derivatives by a pathogenesis-associated type IV secretion system into both bacteria and human cells

Fernández-González E, de Paz HD, Alperi A, Agúndez L, Faustmann M, Sangari FJ, Dehio C, Llosa M. J Bacteriol 193 (22), 6257–6265

[pubmed]

A new family of enzymes catalyzing the first committed step of the methylerythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis in bacteria.

Sangari FJ, Pérez-Gil J, Carretero-Paulet L, García-Lobo JM, Rodríguez-Concepción M. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14081-6. doi: 10.1073/pnas.1001962107.

[pubmed]

Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system.

Viadas C, Rodríguez MC, Sangari FJ, Gorvel JP, García-Lobo JM, López-Goñi I. PLoS One. 2010 Apr 21;5(4):e10216. doi: 10.1371/journal.pone.0010216.

[pubmed]

Brucella abortus ure2 region contains an acid-activated urea transporter and a nickel transport system.

Sangari FJ, Cayón AM, Seoane A, García-Lobo JM. BMC Microbiol. 2010 Apr 10;10:107. doi: 10.1186/1471-2180-10-107.

[pubmed]

Yelina Ortiz Pérez

Asunción Seoane Seoane

IBBTEC

Instituto de Biomedicina y Biotecnología de Cantabria.
PCTCAN - Cl. Albert Einstein, 22
39011 Santander

Félix Sangari García (IP)

Molecular Biology of Brucella Pathogenicity

Research lines

Group history

Funding

Citizen Science to Raise Antimicrobial Resistance Awareness in the Community: The MicroMundo Project in Spain and Portugal.

Effects of vaccination with Brucella melitensis, strains Rev 1 ΔeryCD and Rev 1, on the reproductive system of young male goats

The microbiome of the ice-capped Cayambe Volcanic Complex in Ecuador

Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase

#EUROmicroMOOC: using Twitter to share trends in Microbiology worldwide

Polymorphisms in Brucella Carbonic anhydrase II mediate CO2 dependence and fitness in vivo.

Twitter as a Tool for Teaching and Communicating Microbiology: The #microMOOCSEM Initiative.

The exploration of Brucella transcriptome: From the ORFeome to RNAseq (book).

Evaluation of the effects of erythritol on gene expression in Brucella abortus.

Transfer of R388 derivatives by a pathogenesis-associated type IV secretion system into both bacteria and human cells

A new family of enzymes catalyzing the first committed step of the methylerythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis in bacteria.

Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system.

Brucella abortus ure2 region contains an acid-activated urea transporter and a nickel transport system.

Yelina Ortiz Pérez

Asunción Seoane Seoane

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IBBTEC

Félix Sangari García (IP)

​​​​​​​Molecular Biology of Brucella Pathogenicity

Research lines

Group history

Funding

Citizen Science to Raise Antimicrobial Resistance Awareness in the Community: The MicroMundo Project in Spain and Portugal.

Effects of vaccination with Brucella melitensis, strains Rev 1 ΔeryCD and Rev 1, on the reproductive system of young male goats

The microbiome of the ice-capped Cayambe Volcanic Complex in Ecuador

Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase

#EUROmicroMOOC: using Twitter to share trends in Microbiology worldwide

Polymorphisms in Brucella Carbonic anhydrase II mediate CO2 dependence and fitness in vivo.

Twitter as a Tool for Teaching and Communicating Microbiology: The #microMOOCSEM Initiative.

The exploration of Brucella transcriptome: From the ORFeome to RNAseq (book).

Evaluation of the effects of erythritol on gene expression in Brucella abortus.

Transfer of R388 derivatives by a pathogenesis-associated type IV secretion system into both bacteria and human cells

A new family of enzymes catalyzing the first committed step of the methylerythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis in bacteria.

Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system.

Brucella abortus ure2 region contains an acid-activated urea transporter and a nickel transport system.

Yelina Ortiz Pérez

Asunción Seoane Seoane

Sobre nosotros

Eventos

Contacto

Login

About us

Events

Contact

Login

IBBTEC

Molecular Biology of Brucella Pathogenicity