Fuencisla Pilar is Assistant Professor of Pharmacology and member of the Research Group "Neurobiological Bases of the Mechanism of Action of Drugs acting on the Central Nervous System" of the Institute of Biomedicine and Biotechnology of Cantabria, University of Cantabria and the group CB/07/09/0029 of the Biomedical Research Networking Centres of Mental Health (CIBERSAM), led by Professor Ángel Pazos. Dr. Pilar obtained the Bachelor's Degree in Biological Sciences from the University of León in 1998 and the Doctorate from the same University in 2006 in the field of neuroscience. In 2007, she joined Prof. Pazos' group (University of Cantabria, UC), as a CIBERSAM researcher. During that period, she focused her research on the role of modulation of 5-HT2A receptors in the treatment of depression, in addition to the involvement of neuroplastic processes in the antidepressant effect. In 2011, she carried out a postdoctoral stay in the Molecular Pharmacology group of Dr. González-Maeso (Mount Sinai School of Medicine, New York, USA), studying of the implication of the 5-HT2A/mGlu2 dimer in the neurobiology of schizophrenia. Currently, her research activity is focused on the study of the mechanism of action of fast-acting antidepressant drugs such as cannabidiol and ketamine, focusing on aspects related to neuroplasticity and neuroinflammation. She is co-IP of two national projects SAF2015-67457-R and RTI2018-097534-B-I00. Regarding the academic activity, she teaches Pharmacology in the Degree of Medicine and the "Master's Degree in Initiation in Research in Mental Health" (CIBERSAM) and "Master's Degree in Molecular Biology and Medicine" (UC/UPV). She is also secretary of the Bioethics Committee of the UC.
For this purpose, studies in laboratory animals, models of depression and psychosis, and in blood and postmortem samples from depressed and schizophrenic patients are carried out. Behavioural, pharmacological (in vivo assays, receptor labeling), cell biology (immunocytochemistry, neurogenesis), biochemical (second messengers, G proteins), electrophysiological (in vivo and slice recordings) and molecular approaches (gen silencing, transfected receptors) are used.
Instituto de Biomedicina y Biotecnología de Cantabria.
PCTCAN - Cl. Albert Einstein, 22