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Josephine Hotten

  • IBBTEC. c/ Albert Einstein, 22. 39011 Santander (Spain)
  • josephine.hotten@gmx.de
  • (+34) 942 206799 ext. 25914
  • Bacterial Type IV Secretion Systems
  • Microbiology & Genomics
  • Department of Microbiology & Genomics

​Josephine graduated from the University of Applied Sciences Bremerhaven, Germany, with a degree in Marine Biotechnology (2020–2024). During her undergraduate studies, she carried out a project on algal cryopreservation at the Culture Collection of Algae and Protozoa in Oban, Scotland. She developed her bachelor’s thesis at the Leibniz Centre for Tropical Marine Research in Bremen, Germany, as part of a project on the detection of MAA genes in jellyfish. She is currently pursuing a Master’s degree in Biotechnology at the University of Applied Sciences Bremerhaven. For her master’s thesis, she joined the group of Matxalen Llosa in September 2025 with the support of a JAE Intro ICU fellowship and an Erasmus+ scholarship.​​

​​​​​​Biology of Bacterial Type IV Secretion Systems





Research lines 

    •  Use of bacterial secretion systems for the genomic modification of human cells
    •  Site-specific recombination and integration catalyzed by conjugative relaxases 
    •  Substrate Recruitment by Type IV Secretion systems 

Funding:

    • MINECO BIO2017-87190-R, “Secreción de ADN de bacterias a células de mamífero. Análisis de su papel en virulencia y su potencial aplicación terapéutica”. IP: Matxalen Llosa
    • AECC IDEAS211LLOS, "Papel de la secreción de ADN bacteriano en el desarrollo tumoral". IP: Matxalen Llosa
    • SODERCAN/FEDER JU06. “Reclutamiento de Proteínas y ADN por sistemas de secreción Tipo IV A y B”. IP: Matxalen Llosa

Lab Retreat 2019

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Lab Retreat 2018

 







Matxalen Llosa Blas (IP)

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Pablo Guridi Fernández

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Dolores Lucía Guzmán Herrador

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