Lorena García Gaipo

  • lorena.garcia@unican.es
  • 942 206 799 ext. 25904
  • Transcriptional Control of Cancer and Cells and Stem Cells
  • Cancer
  • Department of Cell & Molecular Signalling

Lorena García Gaipo obtained her Degree in Biology at the University of León and her Master's Degree in Molecular Biology and Biomedicine at the University of Cantabria. Currently, she is completing her PhD under the supervision of Dolores Delgado and Javier León. Her research work is focused on investigating the role of CTCF in the regulation of erythroid cell differentiation in human hematopoietic cells and the effects of epigenetic drugs in the treatment of aggressive B-cell lymphomas.


​Transcriptional Control in Cancer Cells and Stem Cells

Research lines

    • Roles of MYC network proteins MNT and MXD on cell proliferation  
    • Functional interactions of MYC with cell cycle regulatory proteins
    • MYC target genes in leukemia/lymphoma 
    • Function of the chromatin regulator CTCF in the hematopoietic differentiation
    • CTCF involvement in hematological malignancies, especially in lymphomas. 
    • CTCF regulation of MYCand BCL6 oncogenes.

Funding 

    • Oncoproteínas MYC Y CTCF en el control transcripcional de la diferenciación hematopoyética y en linfoma. SAF2014-53526R. CoIPs: Javier León y M. Dolores Delgado
    • Función de los reguladores transcripcionales CTCF y CTCF-L (BORIS) en la diferenciación hematopoyética normal y patológica. Instituto de Salud Carlos III. FIS11/00397
    • Terapia epigenética en linfomas de células B. Papel de los reguladores de cromatina de la familia CTCF. Entidad financiadora: Celgene S.L.U.
    • "Red Temática Investigación Cooperativa de Investigación en Cáncer" ISCIII-RETIC RD12/0036/0033. IP: Piero Crespo
    • "Functional interaction of MYC and CTCF in aggressive B-cell lymphoma and hematopoietic precursors" SAF2017-88026-R. CoIPs: M. Dolores Delgado y Javier León


Javier León Serrano (IP)

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Mª Dolores Delgado Villar (IP)

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Vanessa Junco Ruisánchez

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