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Pablo Duque Dorado

  • IBBTEC. C/ Albert Einstein 22, PCTCAN, 39011 Santander (Spain)
  • duquep@unican.es
  • (+34) 942 206 799 - Ext. 25918
  • Protein Design and Engineering
  • Structural Biology
  • Department of Microbiology & Genomics

​Pablo Duque Dorado is a Predoctoral Investigator at the Protein Design and Engineering Group (IBBTEC) as well as the Clinical and Translational Research Group in Digestive Diseases (IDIVAL). Having graduated with an Honorific Mention from secondary school in 2019, he acquired his Bachelor’s Degree in Biotechnology at the Polytechnic University of Valencia (UPV) in 2023 with a semester-long ERASMUS+ stay in Brno, Czech Republic in his curriculum (2022-2023). He then proceeded to study his Master’s Degree in Research in Immunology (2023-2024) at the Complutense University of Madrid (UCM), and developed a 7 month internship as a research assistant at the Cajal Institute (Madrid) after receiving a JAE Intro grant by the Spanish National Research Council (CSIC), which was performed under the tutoring of Dr. Mª Ángeles Arévalo from the Neuroactive Steroids group; he also carried out his Master’s thesis at this group. Mr. Duque is currently developing his doctoral studies under the guidance of Dr. María Jesús Lucas Gay (Associated Professor at the UC and Principal Investigator of her group at the IBBTEC) and Dr. Marta Alonso Peña (Assistant Professor at the UC and Investigator at her group at the IDIVAL), studying the functional and structural characteristics of genetic variants in liver disease of unknown origin.​​

​​​​​​​​​​​​Protein Design and Engineering

​PIs: Gabriel Moncalián & María Lucas Gay




Research Lines

    • Structure, function and modification of polyunsaturated fatty acid synthases.
    • Optimization of the microbial production of added value fatty acids and triglycerides.
    • Optimization of proteins involved in bacterial conjugation for biotechnological applications. 
    • Structure and function of protein complexes involved in intracellular vesicular traffic.
    • Molecular and structural basis of neurodegenerative diseases.
    • Structural basis of Host-Pathogen Interactions.


Services offered 

    • Design and optimization of proteins with biotechnological, biomedical or industrial interest. 
    • Structural analysis of proteins by X-ray crystallography and in silico molecular threading.


Funding 


    • EUNICE - European University for Customised Education. 101004083-EUNICE-EAC-A02-2 
    • REUNICE RESEARCH WITH AND FOR SOCIETY IN EUNICE. H2020-IBA-SfS-2-2020-101035813
    • Plataforma de cromatografía acoplada a espectrometría de masas (EQC2021-007113-P) 
    • Microscopio electronico de transmisión de ultima generacion para el análisis estructural de macromoleculas biologicas (EQC2021-007003-P) 
    • Modificación de megasintasas para la producción de precursores químicos sostenibles (TED2021-129278B-I00) 
    • Megasintasas de acidos grasos poliinsaturados: estructura, optimizacion y aplicaciones (PID2021-122164NB-I00)
    • Mecanismo de acción del complejo Retriever (PID2021-122611NB-I00)​


Gabriel Moncalián (IP)

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María Lucas Gay (IP)

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Arturo García López

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Nahuel Ismael Lofeudo Álvarez

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Iván Méndez Guzmán

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