A drug, in order to be authorized for the treatment or prevention of diseases in humans or animals, has to go through several stages of investigation, to demonstrate its quality, efficacy and safety. One of these stages is pre-clinical trials, where molecules with potential to be a drug candidate are studied in models in vitro and in experimental animals, in order to know the effects of the compound in the different organs and systems. The main objective of this stage is to rigorously evaluate the efficiency expectations and the safety profile of the compound before beginning clinical trials in humans.
The IBBTEC has the capacities, the human team and the experience necessary to carry out Preclinical evaluation Projects of biological activity of different compounds and molecules of natural and synthetic origin, as well as to validate new therapeutic targets for the discovery of drugs. The main areas of specialization are:
• Neuropsychiatry: Depression/anxiety, schizophrenia and chronic pain
• Immunology: inflammation, especially neuroinflammation
• Infectious diseases: Antibiotic resistance
• Toxicology: Toxicity and Teratogenicity
The miniaturization, simplification and automation of the analytical systems has given rise to the so-called lab-on-A-Chip, which aims to integrate the main analytical processes carried out in a laboratory (mixing, reaction, injection, separation, detection, etc...) In a small-sized device. Microfluidics is a part of Lab-on-A-Chip technologies that has been developed in parallel, becoming a new field of research. These devices provide high analytical speeds, great versatility, high efficiency and low cost, opening up the possibility of parallel testing, decreasing sample consumption and reagents, as well as generating Waste.
The IBBTEC It has the capacities, the human team and the experience necessary to carry out Projects to design and manufacture microfluidic and electronic systems, allowing the development of new technologies for biomedical applications, including new experimental measuring systems, diagnostic devices or biotechnological interest.
Protein purification is a process by which a protein can be isolated from a complex mixture. This process is fundamental in biomedical and biotechnology research, to study and characterize the function, structure and molecular interactions of a protein of interest, such as an enzyme, a cell receptor or an antibody.
IBBTEC has the capacities, the human team and the experience necessary to carry out Projects of expression and purification of proteins and macromolecular complexes, in order to obtain samples with a high degree of purity and homogeneity that allow to carry out biochemical tests of activity and/or a structural analysis by X-ray crystallography or electron microscopy.
Instituto de Biomedicina y Biotecnología de Cantabria.
PCTCAN - Cl. Albert Einstein, 22