| Seed-directed growth of gold nanostars on paper via inkjet-printing for the development of a sensitive glucose sensor | | Seed-directed growth of gold nanostars on paper via inkjet-printing for the development of a sensitive glucose sensor | Ortiz-Gómez I, Calderón Celis F, Costa-Fernández JM, Fernández-Lodeiro C, Lodeiro C, Fernández-Lodeiro J. | 2025-10-10T22:00:00Z | <h2>Abstract<br></h2><p>This study presents a reliable, biodegradable, and cost-effective colorimetric glucose sensor developed through the in situ growth of nanostar-shaped gold nanostructures on a paper-based analytical device (PAD). Gold seeds were precisely deposited onto cellulose fibers via inkjet printing, enabling controlled growth through a seed-mediated approach, with adenosine monophosphate (AMP) acting as a morphology-directing agent. The localized and controlled growth of these nanostructures within the cellulose matrix ensures a uniform nanocatalytic surface, while maintaining the scalability and reproducibility required for low-cost sensor fabrication. The optimized PAD exhibited a homogeneous plasmonic surface, allowing for sensitive glucose detection through visible color changes. A linear response was achieved over a glucose concentration range of 1 to 200 µM, with a detection limit of 0.56 µM, highlighting its potential for Point-Of-Care (POC) diagnostic applications. The resulting PAD also offers a portable and multifunctional platform for colorimetric glucose analysis. Furthermore, its practical design and robust performance enable real-time glucose monitoring using only a smartphone to capture the PAD’s color change and correlate it with the glucose concentration.<br></p> | <p><a href="https://doi.org/10.1016/j.greeac.2025.100305" target="_blank">Green Anal. Chem. 2025 Oct 11, Vol 15, 100305</a><br></p> | 521 | | |
