New Insights in Radiotherapy

Article

Biomedicines 2022, 10, 1931

 Authorship: CARLOS MANUEL MARTINEZ CAMPA

 09/08/2022

Melatonin modulation of radiation-induced molecular changes in MCF-7 human breast cancer cells

Article

Biomedicines 2022, 10(5), 1088

 Authorship: CAROLINA ALONSO GONZALEZ, CRISTINA GONZÁLEZ ABALDE, JAVIER MENÉNDEZ MENÉNDEZ, ALICIA GONZÁLEZ GONZÁLEZ, VIRGINIA ALVAREZ GARCIA, ALICIA VERONICA GONZALEZ CABEZA, CARLOS MANUEL MARTINEZ CAMPA, SAMUEL COS CORRAL

 07/05/2022

Melatonin as an adjuvant to antiangiogenic cancer treatments

Article

Cancers, 2021, 13(13), 3263

 Authorship: ALICIA VERONICA GONZALEZ CABEZA, CAROLINA ALONSO GONZALEZ, ALICIA GONZALEZ GONZALEZ, JAVIER MENÉNDEZ MENÉNDEZ, SAMUEL COS CORRAL, CARLOS MANUEL MARTINEZ CAMPA

 2021

Editorial for the special issue “new strategies in cancer pharmacotherapy: Development of hormonal antineoplastic drugs, cytotoxic drugs and targeted therapies”

Article

Int J Mol Sci . 2020 Jun 8;21(11):4081

 Authorship: CARLOS MANUEL MARTINEZ CAMPA, CAROLINA ALONSO GONZALEZ

 2020

Usefulness of melatonin as complementary to chemotherapeutic agents at different stages of the angiogenic process

Article

Scientific Reports volume 10, Article number: 4790 (2020)

 Authorship: ALICIA GONZÁLEZ- GONZÁLEZ, NOEMI RUEDA REVILLA, CAROLINA ALONSO GONZALEZ, JAVIER MENÉNDEZ MENÉNDEZ, CARLOS MANUEL MARTINEZ CAMPA, STEFANIA MITOLA, SAMUEL COS CORRAL

 2020

Melatonin as a Radio-Sensitizer in Cancer

Article

Biomedicines 2020, 8(8), 247

 Authorship: CAROLINA ALONSO GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, JAVIER MENÉNDEZ MENÉNDEZ, CARLOS MANUEL MARTINEZ CAMPA, SAMUEL COS CORRAL

 2020

Deciphering the molecular basis of melatonin protective effects on breast cells treated with doxorubicin: TWIST1 a transcription factor involved in EMT and metastasis, a novel target of melatonin

Article

Cancers, 2019, 11(7), 1011

 Authorship: JAVIER MENÉNDEZ-MENÉNDEZ, FRANCISCO HERMIDA-PRADO, ROCÍO GRANDA-DÍAZ, ALICIA VERONICA GONZALEZ CABEZA, JUANA MARÍA GARCÍA-PEDRERO, NAGORE DEL-RÍO-IBISATE, ALICIA GONZÁLEZ-GONZÁLEZ, SAMUEL COS CORRAL, CAROLINA ALONSO GONZALEZ, CARLOS MANUEL MARTINEZ CAMPA

 2019

Melatonin Enhances the Usefulness of Ionizing Radiation: Involving the Regulation of Different Steps of the Angiogenic Process

Article

Front Physiol. 2019; 10: 879

 Authorship: ALICIA GONZÁLEZ-GONZÁLEZ, ALICIA VERONICA GONZALEZ CABEZA, NOEMI RUEDA REVILLA, CAROLINA ALONSO GONZALEZ, JAVIER MENÉNDEZ-MENÉNDEZ, JOSE EZEQUIEL GOMEZ AROZAMENA, CARLOS MANUEL MARTINEZ CAMPA, SAMUEL COS CORRAL

 2019

Melatonin Modulation of Radiation and Chemotherapeutics-induced Changes on Differentiation of Breast Fibroblasts

Article

Int J Mol Sci. 2019 Aug; 20(16): 3935

 Authorship: ALICIA GONZÁLEZ-GONZÁLEZ, ENRIQUE GARCÍA NIETO, ALICIA VERONICA GONZALEZ CABEZA, CRISTINA SANCHEZ FERNANDEZ, CAROLINA ALONSO GONZALEZ, JAVIER MENÉNDEZ-MENÉNDEZ, JOSE EZEQUIEL GOMEZ AROZAMENA, SAMUEL COS CORRAL, CARLOS MANUEL MARTINEZ CAMPA

 2019

Melatonin enhances the apoptotic effects and modulates the changes in gene expression induced by docetaxel in MCF 7 human breast cancer cells

Article

Int J Oncol. 2018 Feb;52(2):560-570

 Authorship: CAROLINA ALONSO GONZALEZ, JAVIER MENÉNDEZ MENÉNDEZ, ALICIA GONZALEZ GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, SAMUEL COS CORRAL, CARLOS MANUEL MARTINEZ CAMPA

 01/02/2018

Complementary actions of melatonin on angiogenic factors, the angiopoietin/Tie2 axis and VEGF, in co-ultures of human endothelial and breast cancer cells

Article

Oncol Rep. 2018 Jan;39(1):433-441

 Authorship: ALICIA GONZALEZ GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, CAROLINA ALONSO GONZALEZ, JAVIER MENÉNDEZ MENÉNDEZ, CARLOS MANUEL MARTINEZ CAMPA, SAMUEL COS CORRAL

 01/01/2018

Melatonin enhances chemosensitivity of human endothelial and breast cancer cells by regulating genes involved in angiogenesis

Conference object

J Cancer Sci Ther 2018, Vol.10: 40

 Authorship: ALICIA GONZALEZ GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, CAROLINA ALONSO GONZALEZ, CARLOS MANUEL MARTINEZ CAMPA, JAVIER MENÉNDEZ MENÉNDEZ, SAMUEL COS CORRAL

 2018

Effects of melatonin on chemotherapy treatments in gene expression and proteomics of human breast cancer cells

Conference object

J Cancer Sci Ther 2018, Vol.10: 41

 Authorship: JAVIER MENÉNDEZ MENÉNDEZ, CARLOS MANUEL MARTINEZ CAMPA, CAROLINA ALONSO GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, ALICIA GONZALEZ GONZALEZ, SAMUEL COS CORRAL

 2018

Enhancement of radiosensitivity of human endothelial and breast cancer cells with melatonin by regulating angiogenesis and genes involved in estrogen biosynthesis

Conference object

Breast Cancer: Current Research, 2017, 2(S3), 60

 Authorship: ALICIA GONZALEZ GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, CAROLINA ALONSO GONZALEZ, CARLOS MANUEL MARTINEZ CAMPA, JAVIER MENÉNDEZ MENÉNDEZ, SAMUEL COS CORRAL

 01/06/2017

The ABC7 regimen: a new approach to metastatic breast cancer using seven common drugs to inhibit epithelial-to-mesenchymal transition and augment capecitabine efficacy.

Article

Breast Cancer, 2017, 9, 495-514

 Authorship: RICHARD E. KAST, NICOLAS SKULI, SAMUEL COS CORRAL, GEORG KARPEL MASSLER, YUSUKE SHIOZAWA, RAN GOSHEN, MARC-ERIC HALATSCH

 2017

Signalling Pathways Targeted by Melatonin in Cancer. A Short Review

Article

J Tumor Med Prev 1(4): JTMP.MS.ID.555570 (2017)

 Authorship: CARLOS MANUEL MARTINEZ CAMPA, JAVIER MENÉNDEZ MENÉNDEZ, CAROLINA ALONSO GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, ALICIA GONZALEZ GONZALEZ, SAMUEL COS CORRAL

 2017

What is known about melatonin, chemotherapy and altered gene expression in breast cancer

Article

Oncol Lett. 2017 Apr;13(4):2003-2014

 Authorship: ALICIA VERONICA GONZALEZ CABEZA, ALICIA GONZALEZ GONZALEZ, CAROLINA ALONSO GONZALEZ, JAVIER MENÉNDEZ MENÉNDEZ, CARLOS MANUEL MARTINEZ CAMPA, SAMUEL COS CORRAL

 01/04/2017

Melatonin inhibits angiogenesis in SH-SY5Y human neuroblastoma cells by downregulation of VEGF.

Article

Oncol Rep. 2017 Apr;37(4):2433-2440

 Authorship: ALICIA VERONICA GONZALEZ CABEZA, ALICIA GONZALEZ GONZALEZ, CAROLINA ALONSO GONZALEZ, JAVIER MENÉNDEZ MENÉNDEZ, CARLOS MANUEL MARTINEZ CAMPA, SAMUEL COS CORRAL

 01/04/2017

Melatonin as Modulator of Radiosensibility and Chemosensibility in Cancer

Book part

Pineal Gland: Research Advances and Clinical Challenges

 Authorship: CAROLINA ALONSO GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, SAMUEL COS CORRAL, ALICIA GONZALEZ GONZALEZ, JAVIER MENÉNDEZ MENÉNDEZ, CARLOS MANUEL MARTINEZ CAMPA

 2017

Melatonin Inhibits the Growth of DMBA-induced Mammary Tumors by Regulating Estrogen Sulfatase Enzyme

Book part

Advances in Cancer Drug Targets. Volume 3

 Authorship: ALICIA VERONICA GONZALEZ CABEZA, VIRGINIA ALVAREZ GARCIA, CARLOS MANUEL MARTINEZ CAMPA, CAROLINA ALONSO GONZALEZ, SAMUEL COS CORRAL

 2016

Regulation of angiopoietins, tie-2 and vascular endothelial growth factor by melatonin in human breast cancer and endothelial cells

Conference object

J Physiol Biochem (2016) 72 (Suppl 1):S54

 Authorship: ALICIA GONZALEZ GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, CAROLINA ALONSO GONZALEZ, CARLOS MANUEL MARTINEZ CAMPA, JAVIER MENÉNDEZ MENÉNDEZ, SAMUEL COS CORRAL

 2016

Sensitizing effects of melatonin on docetaxel treatment in human breast cancer cells (MCF-7)

Conference object

J Physiol Biochem (2016) 72 (Suppl 1):S78-79

 Authorship: JAVIER MENÉNDEZ MENÉNDEZ, CAROLINA ALONSO GONZALEZ, ALICIA GONZALEZ GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, SAMUEL COS CORRAL, CARLOS MANUEL MARTINEZ CAMPA

 2016

Melatonin enhancement of the radiosensitivity of human breast cancer cells is associated with the modulation of proteins involved in estrogen biosynthesis

Article

Cancer Letters, 2016, 370(1), 145-152

 Authorship: CAROLINA ALONSO GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, CARLOS MANUEL MARTINEZ CAMPA, JAVIER MENÉNDEZ MENÉNDEZ, JOSE EZEQUIEL GOMEZ AROZAMENA, ÁNGELA GARCÍA VIDAL, SAMUEL COS CORRAL

 01/01/2016

Melatonin: Antiproliferative Actions, Protection of Normal Tissue and Enhancement of Radiosensitivity of Breast Cancer Cells

Article

J Cell Sci Ther 2016, 7:2: 241

 Authorship: CARLOS MANUEL MARTINEZ CAMPA, CAROLINA ALONSO GONZALEZ, ALICIA VERONICA GONZALEZ CABEZA, ALICIA GONZALEZ GONZALEZ, JAVIER MENÉNDEZ MENÉNDEZ, SAMUEL COS CORRAL

 2016

ESTUDIO DE LAS ALTERACIONES MOLECULARES INDUCIDAS POR LA QUIMIOTERAPIA EN EL CANCER DE MAMA. UTILIZAD DE LA MELATONINA COMO ADYUVANTE (CONVOCATORIA FINANCIADA CONTRATO PROGRAMA GOB CANTABRIA -UC)

 DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

Head: SAMUEL COS CORRAL

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2022

Melatonin regulation of the molecular changes induced by chemotherapeutic agents in chemoresistant breast cancer cells

 DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

Head: ALICIA VERONICA GONZALEZ CABEZA

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2021

LA MELATONINA COMO REGULADOR DE LAS VÍAS DE SEÑALIZACIÓN INTRACELULAR Y CAMBIOS MOLECULARES INDUCIDOS POR LA QUIMIOTERAPIA EN EL CÁNCER DE MAMA (CONSEJERÍA DE UNIVERSIDADES, IGUALDAD, CULTURA Y DEPORTE DEL GOBIERNO DE CANTABRIA)

 DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

Head: SAMUEL COS CORRAL

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2020

ESTUDIO DE LOS EFECTOS SENSIBILIZADORES DE LA MELATONINA A LA QUIMIOTERAPIA NEOADYUVANTE EN EL TRATAMIENTO DEL CÁNCER DE MAMA

 DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

Head: CAROLINA ALONSO GONZALEZ

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2017

EFECTOS BENEFICIOSOS DE LA MELATONINA COMO ADYUVANTE EN EL TRATAMIENTO DEL CÁNCER DE MAMA: REGULACIÓN DEL MICROAMBIENTE TUMORAL (SAF2016-77103-P) (AEI/FEDER, UE)

 DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

Heads: SAMUEL COS CORRAL, CARLOS MANUEL MARTINEZ CAMPA

Typology: Competitive national public projects

Start year: 2016

INFLUENCIA DE LA MELATONINA EN LA RADIOSENSIBILIDAD DE LAS CELULAS TUMORALES Y PERITUMORALES MAMARIAS

 DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

Head: SAMUEL COS CORRAL

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2014

EFECTOS SENSIBILIZADORES DE LA MELATONINA A LA QUIMIOTERAPIA Y LA RADIOTERAPIA: ESTUDIO DE LOS CAMBIOS MOLECULARES QUE MODULAN ESTE PROCESO (SAF2013-42012-P) (MINECO)

 DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

Heads: SAMUEL COS CORRAL, CARLOS MANUEL MARTINEZ CAMPA

Typology: Competitive national public projects

Start year: 2014

MELATONINA Y CANCER MAMARIO: ACCIONES ANTEESTROGENICAS DE LA MELATONINA EN EL TEJIDO PERITUMORAL MAMARIO (SAF2010-19759)

 DEPARTAMENTO DE FISIOLOGÍA Y FARMACOLOGÍA

Head: SAMUEL COS CORRAL

Typology: Competitive national public projects

Start year: 2011

LA MELATONINA COMO MODULADOR DE LOS CAMBIOS MOLECULARES INDUCIDOS POR LA RADIOTERAPIA Y LA QUIMIOTERAPIA EN EL CANCER DE MAMA

 Authorship: JAVIER MENÉNDEZ MENÉNDEZ

 Supervision: CARLOS MANUEL MARTINEZ CAMPA , CAROLINA ALONSO GONZALEZ 

 Defense date: 18/01/2021

EFECTOS SENSIBILIZADORES DE LA MELATONINA A LA QUIMIOTERAPIA Y A LA RADIOTERAPIA EN EL CANCER DE MAMA: ACCIONES ANTIANGIOGÉNICAS Y ADIPOGÉNICAS

 Authorship: ALICIA GONZÁLEZ GONZÁLEZ

 Supervision: SAMUEL COS CORRAL , ALICIA VERONICA GONZALEZ CABEZA 

 Defense date: 13/09/2019

Acciones Oncostáticas de la Melatonina en Modelos in Vitro de Tejido Tumoral y Peritumoral Mamario

 Authorship: VIRGINIA ALVAREZ GARCIA

 Supervision: SAMUEL COS CORRAL , CARLOS MANUEL MARTINEZ CAMPA 

 Defense date: 11/04/2013

Caracterización de los Efectos Estrogénicos del Cadmio y del Papel Modulador de la Melatonina sobre los Mismos.

 Authorship: CAROLINA ALONSO GONZALEZ

 Supervision: MARIA DOLORES MEDIAVILLA AGUADO, EMILIO JOSE SANCHEZ BARCELO

 Defense date: 10/03/2009

Alteraciones del Sistema Circadiano en Pacientes con Retinosis Pigmentaria.

 Authorship: MIGUEL ANGEL GORDO VEGA

 Supervision: EMILIO JOSE SANCHEZ BARCELO

 Defense date: 12/12/2003

Análisis de la Influencia in Vitro de Bajas Dosis de Radiación Producidas por 222-Rn sobre Proliferación Celular, Apoptosis y Respuesta a Agentes Citotóxicos.

 Authorship: CARLOS SAINZ FERNANDEZ

 Supervision: JESUS SOTO TORRES, SAMUEL COS CORRAL 

 Defense date: 25/10/2002