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ANA VICTORIA VILLAR RAMOS

Publications
34
Projects
17
Thesis
6
Patents and technologies
3
Datasets
2

anavictoria.villar@unican.es

Edificio IBBTEC. c/ Albert Einstein, 22 (PCTCAN). 39011 Santander

Profesor Titular de Universidad

Doctor en Ciencias Químicas

Laboratorio De Investigación En Tratamientos Moleculares Contra La Fibrosis Cardiaca - FIBROHEART

INST. DE BIOMEDICINA Y BIOTECNOLOGÍA DE CANTABRIA

Specialty areas: FARMACOLOGIA

Identifiers

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Publications Projects Supervised Theses Patents and technologies Datasets

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34 results

1 of 2

Cardiac fibrosis inhibitor CTPR390 prevents structural and morphological changes in human engineered cardiac connective tissue

Article

iScience, 2025, 28(8), 113013

Authorship: DAVID MAESTRO LAVIN, ANA ROSA PALANCA CUÑADO, HELENA SOTO PEREZ-CEJUELA, I. LLARENA, ALISA NICOLE DEGRAVE, GABRIELA GUEDES, GUILHERME HENRIQUE DE OLIVEIRA, ANDRÉ LULIZ COELHO CONCEIÇAO, VERONICA MIEITES ALONSO, JOSE MANUEL ICARDO DE LA ESCALERA, CARLOS SÁNCHEZ-CANO, OLGA MARIA CONDE PORTILLA, SUSANNE LUTZ, AITZIBER L. CORTAJARENA, ANA VICTORIA VILLAR RAMOS

15/08/2025

Fibroblast-derived extracellular vesicles as trackable efficient transporters of an experimental nanodrug with fibrotic heart and lung targeting

Article

Theranostics, 2024, 14(1), 176-202

Authorship: JORGE RUIZ DEL RIO, GABRIELA GUEDES, DANIELLE NOVILLO, ELENA LECUE, ANA ROSA PALANCA CUÑADO, AITZIBER L. CORTAJARENA, ANA VICTORIA VILLAR RAMOS

2024

Short telomeres in alveolar type II cells associate with lung fibrosis in post COVID-19 patients with cancer

Article

Aging, 2023, 15(11), 4625-4641

Authorship: PAULA MARTÍNEZ, RAÚL SÁNCHEZ-VAZQUEZ, ARPITA SAHA, MARIA S. RODRIGUEZ-DUQUE, SARA NARANJO GOZALO, JOY S. OSORIO-CHAVEZ, ANA VICTORIA VILLAR RAMOS, MARIA A. BLASCO

2023

The TGF-ß pseudoreceptor BAMBI as a new therapeutic target to treat abdominal atherosclerotic aortic aneurysm

Conference object

British Journal of Pharmacology, 2023, 180(S1), 84-85

Authorship: RAQUEL GARCIA LOPEZ, VALENTIN TASCON QUEVEDO, LYDIA FRAYLE, ANA VICTORIA VILLAR RAMOS, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA

2023

Profibrotic role of inducible heat shock protein 90a isoform in systemic sclerosis

Article

The Journal of immunology, 2022, 209(1), 38-48

Authorship: JORGE RUIZ DEL RIO, PEDRO MUÑOZ, PATRICIA CARREIRA, JOSÉ L. PABLOS, ANA ROSA PALANCA CUÑADO, JESUS MERINO PEREZ, ANNA SERRANO-MOLLAR, RAMON MERINO PEREZ, ESTHER TAMAYO REVUELTA, MARCOS LOPEZ HOYOS, FEDERICO DÍAZ-GONZÁLEZ, VICTOR MANUEL MARTINEZ TABOADA, ANA VICTORIA VILLAR RAMOS

2022

Epigenetic alterations of TGFß and its main canonical signaling mediators in the context of cardiac fibrosis

Article

Journal of Molecular and Cellular Cardiology. Volume 159, October 2021, Pages 38-47

Authorship: LUIS ALGECIRAS JIMÉNEZ, ANA ROSA PALANCA CUÑADO, DAVID MAESTRO LAVIN, JORGE RUIZ DEL RIO, ANA VICTORIA VILLAR RAMOS

2021

Correlative 3D cryo X-ray imaging reveals intracellular location and effect of designed antifibrotic protein-nanomaterial hybrids

Article

Chemical Science, 2021, 12(45), 15090-15103

Authorship: J. GROEN, ANA ROSA PALANCA CUÑADO, A. AIRES, J.J. CONESA, DAVID MAESTRO LAVIN, S. REHBEIN, M. HARKIOLAKI, ANA VICTORIA VILLAR RAMOS, A.L. CORTAJARENA, E. PEREIROA

19/10/2021

Engineering multifunctional metal/protein hybrid nanomaterials as tools for therapeutic intervention and high-sensitivity detection

Article

Chemical Science, 2021,12, 2480-2487

Authorship: ANTONIO AIRES, DAVID MAESTRO LAVIN, JORGE RUIZ DEL RIO, ANA ROSA PALANCA CUÑADO, ELENA LÓPEZ MARTÍNEZ, IRANTZU LLARENA, KALOTINA GERAKI, CARLOS SÁNCHEZ CANO, ANA VICTORIA VILLAR RAMOS, AITZIBER L. CORTAJARENA

2021

Sex-specific regulation of miR-29b in the myocardium under pressure overload is associated with differential molecular, structural and functional remodeling patterns in mice and patients with aortic stenosis

Article

Cells, 2020, 9(4), 833

Authorship: RAQUEL GARCIA LOPEZ, ANA B. SALIDO MEDINA, ARITZ GIL, DAVID MERINO, JENNY GÓMEZ, ANA VICTORIA VILLAR RAMOS, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, FRANCISCO JESUS GONZALEZ VILCHEZ

30/03/2020

Biological Membranes in EV Biogenesis, Stability, Uptake, and Cargo Transfer: an ISEV Position Paper Arising From the ISEV Membranes and EVs Workshop

Article

J Extracell Vesicles . 2019 Nov 8;8(1):1684862

Authorship: ASHLEY E. RUSSELL, ALEXANDRA SNEIDER, KENNETH W. WITWER, PAOLO BERGESE, SUVENDRA N. BHATTACHARYYA, ALEXANDER COCKS, EMANUELE COCUCCI, UTA ERDBRÜGGER, JUAN M. FALCON-PEREZ, DAVID W. FREEMAN, THOMAS M. GALLAGHER, SHUAISHUAI HU, YIYAO HUANG, STEVEN M. JAY, SHIN-ICHI KANO, GREGORY LAVIEU, ALEKSANDRA LESZCZYNSKA, ALICIA M. LLORENTE, QUAN LU, ANA VICTORIA VILLAR RAMOS

2019

Reduction of Cardiac TGFß-mediated Profibrotic Events by Inhibition of Hsp90 With Engineered Protein

Article

J Mol Cell Cardiol , 123, 75-87 Oct 2018

Authorship: R A CÁCERES, T CHAVEZ, DAVID MAESTRO LAVIN, ANA ROSA PALANCA CUÑADO, P BOLADO, F. MADRAZO, A. AIRES, A.L. CORTAJARENA, ANA VICTORIA VILLAR RAMOS

2018

Newly experimental designed CTPR390-488 biosynthetic nanoparticle as a potential biomarker-drug of myocardial fibrosis

Conference object

Cardiovascular Research, 2018, 114(S1), S37

Authorship: ANA ROSA PALANCA CUÑADO, DAVID MAESTRO LAVIN, RA. CACERES, T. CHAVEZ, A. AIRES, AL. CORTAJARENA, ANA VICTORIA VILLAR RAMOS

2018

Estructura y funcionamiento de la supervisión en la EDUC

Conference object

Evaluación de la Calidad de la Investigación y de la Educación Superior: libro de resúmenes XV FECIES Superior, libro de resúmenes, Santander (España), 10-12 de Mayo de 2018

Authorship: MIGUEL SANTIBAÑEZ MARGÜELLO, JOSE RAMOS VIVAS, ERNESTO MADARIAGA DOMINGUEZ, ANA VICTORIA VILLAR RAMOS

2018

Extracellular heat shock protein 90 binding to TGFbeta receptor I participates in TGFbeta-mediated collagen production in myocardial fibroblasts

Article

Cellular Signalling, 2016, 28(10), 1563-1579

Authorship: RAQUEL GARCIA LOPEZ, DAVID MERINO FERNANDEZ, JENNY M GÓMEZ, JUAN FRANCISCO NISTAL HERRERA, MARIA AMOR HURLE GONZALEZ, AITZIBER L. CORTAJARENA, ANA VICTORIA VILLAR RAMOS

2016

BMP-7 attenuates left ventricular remodelling under pressure overload and facilitates reverse remodelling and functional recovery

Article

Cardiovascular Research, 2016, 110(3), 331-345

Authorship: DAVID MERINO FERNANDEZ, ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MONICA TRAMULLAS FERNANDEZ, LUIS RUIZ, CATALINA RIBAS, SOFÍA CABEZUDO, JUAN FRANCISCO NISTAL HERRERA, MARIA AMOR HURLE GONZALEZ

01/04/2016

Desequilibrio de señalización BMP7 frente a TGFB en el remodelado del ventrículo izquierdo por sobrecarga de presión: estudio traslacional

Conference object

Revista Española de Cardiología, 2015, 68(Supl.1), 386

Authorship: JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO GARCÍA, ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MONICA TRAMULLAS FERNANDEZ, LUIS RUIZ GUERRERO, CATALINA RIBAS NÚÑEZ, MARIA AMOR HURLE GONZALEZ

2015

Influencia de la proteína de choque térmico 90 en la expresión de mediadores y dianas profibróticas del factor de crecimiento transformante beta en el corazón sometido a sobrecarga de presión

Conference object

Revista Española de Cardiología, 2015, 68(Supl.1), 1097

Authorship: RAQUEL GARCIA LOPEZ, JENNY GÓMEZ, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, ANA VICTORIA VILLAR RAMOS

2015

The normal balance between antifibrotic Bmp7 and profibrotic Tgfâ signaling is lost on the pressure overloadinduced LV remodeling and can be modified favorably. A translational study

Conference object

Circulation, 2015, 132, A14298

Authorship: JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO FERNANDEZ, ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MONICA TRAMULLAS FERNANDEZ, LUIS RUIZ GUERRERO, CATALINA RIBAS, MARIA AMOR HURLE GONZALEZ

2015

p-SMAD2/3 and DICER promote pre-miR-21 processing during pressure overload-associated myocardial remodeling

Article

Biochimica et Biophysica Acta. Molecular Basis of Disease, 2015, 1852(7), 1520-30

Authorship: RAQUEL GARCIA LOPEZ, JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO FERNANDEZ, NATHAN L PRICE, CARLOS FERNANDEZ HERNANDO, JAVIER BEAUMONT, ARANTXA GONZÁLEZ, MARIA AMOR HURLE GONZALEZ, ANA VICTORIA VILLAR RAMOS

2015

Bone morphogenetic protein 7 protects against pressure overload-induced left ventricular remodeling and facilitates its regression in mice

Conference object

Cardiovascular Research, 2014, 103, S102?S141

Authorship: DAVID MERINO FERNANDEZ, ANA VICTORIA VILLAR RAMOS, JUAN FRANCISCO NISTAL HERRERA, MARIA AMOR HURLE GONZALEZ

2014

Regulación por TGF-B del procesamiento de microRNA-21 por DICER y su papel fisiopatológico en el remodelado VI por sobrecarga de presión en el animal de experimentación y en la clínica

Conference object

Revista Española de Cardiología, 2014, 67( Supl.1), 868

Authorship: JUAN FRANCISCO NISTAL HERRERA, RAQUEL GARCIA LOPEZ, DAVID MERINO FERNANDEZ, MARIA AMOR HURLE GONZALEZ, ANA VICTORIA VILLAR RAMOS

2014

Nueva técnica para la constricción y de-constricción del arco aórtico en ratones; sencilla; segura y controlable; como modelo de hipertrofia por sobrecarga de presión

Conference object

Revista Española de Cardiología, 2014, 67( Supl.1), 1118

Authorship: JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO FERNANDEZ, JENNY GÓMEZ DELGADO, ANA VICTORIA VILLAR RAMOS, MARIA AMOR HURLE GONZALEZ

2014

Metabolismo de los fármacos

Book part

Farmacología humana

Authorship: ANA VICTORIA VILLAR RAMOS, CARMEN DEL ARCO, JESUS FLOREZ BELEDO

2014

Circulating levels of miR-133a predict the regression potential of left ventricular hypertrophy after valve replacement surgery in patients with aortic stenosis

Article

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2013, 2(4), e000211

Authorship: RAQUEL GARCIA LOPEZ, ANA VICTORIA VILLAR RAMOS, MANUEL COBO, MIGUEL LLANO, RAFAEL MARTÍN-DURÁN, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA

2013

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ANA VICTORIA VILLAR RAMOS

Identifiers

Cardiac fibrosis inhibitor CTPR390 prevents structural and morphological changes in human engineered cardiac connective tissue

Fibroblast-derived extracellular vesicles as trackable efficient transporters of an experimental nanodrug with fibrotic heart and lung targeting

Short telomeres in alveolar type II cells associate with lung fibrosis in post COVID-19 patients with cancer

The TGF-ß pseudoreceptor BAMBI as a new therapeutic target to treat abdominal atherosclerotic aortic aneurysm

Profibrotic role of inducible heat shock protein 90a isoform in systemic sclerosis

Epigenetic alterations of TGFß and its main canonical signaling mediators in the context of cardiac fibrosis

Correlative 3D cryo X-ray imaging reveals intracellular location and effect of designed antifibrotic protein-nanomaterial hybrids

Engineering multifunctional metal/protein hybrid nanomaterials as tools for therapeutic intervention and high-sensitivity detection

Sex-specific regulation of miR-29b in the myocardium under pressure overload is associated with differential molecular, structural and functional remodeling patterns in mice and patients with aortic stenosis

Biological Membranes in EV Biogenesis, Stability, Uptake, and Cargo Transfer: an ISEV Position Paper Arising From the ISEV Membranes and EVs Workshop

Reduction of Cardiac TGFß-mediated Profibrotic Events by Inhibition of Hsp90 With Engineered Protein

Newly experimental designed CTPR390-488 biosynthetic nanoparticle as a potential biomarker-drug of myocardial fibrosis

Estructura y funcionamiento de la supervisión en la EDUC

Extracellular heat shock protein 90 binding to TGFbeta receptor I participates in TGFbeta-mediated collagen production in myocardial fibroblasts

BMP-7 attenuates left ventricular remodelling under pressure overload and facilitates reverse remodelling and functional recovery

Desequilibrio de señalización BMP7 frente a TGFB en el remodelado del ventrículo izquierdo por sobrecarga de presión: estudio traslacional

Influencia de la proteína de choque térmico 90 en la expresión de mediadores y dianas profibróticas del factor de crecimiento transformante beta en el corazón sometido a sobrecarga de presión

The normal balance between antifibrotic Bmp7 and profibrotic Tgfâ signaling is lost on the pressure overloadinduced LV remodeling and can be modified favorably. A translational study

p-SMAD2/3 and DICER promote pre-miR-21 processing during pressure overload-associated myocardial remodeling

Bone morphogenetic protein 7 protects against pressure overload-induced left ventricular remodeling and facilitates its regression in mice

Regulación por TGF-B del procesamiento de microRNA-21 por DICER y su papel fisiopatológico en el remodelado VI por sobrecarga de presión en el animal de experimentación y en la clínica

Nueva técnica para la constricción y de-constricción del arco aórtico en ratones; sencilla; segura y controlable; como modelo de hipertrofia por sobrecarga de presión

Metabolismo de los fármacos

Circulating levels of miR-133a predict the regression potential of left ventricular hypertrophy after valve replacement surgery in patients with aortic stenosis