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13 results 
       

IkBalfa controls dormancy induction in Hematopoietic stem cell development via retinoic acid

Article

Nature Communications, 2024, 15(1), 4673

 Authorship: ROSHANA THAMBYRAJAH, MARIA MAQUEDA, MUHAMMAD ZAKI FADLULLAH, MARTIN PROFFITT, WEN HAO NEO, YOLANDA GUILLÉN, MARTA CASADO PELAEZ, PATRICIA HERRERO MOLINERO, CARLA BRUJAS, NOEMI CASTELLUCCIO, JESSICA GONZÁLEZ, ARNAU IGLESIAS, LAURA MARRUECOS, CRISTINA RUIZ HERGUIDO, MANEL ESTELLER, ELISABETTA MEREU, GEORGES LACAUD, LLUIS ESPINOSA, ANNA BIGAS

 2024

In the spotlight: the role of TGFbeta signalling in haematopoietic stem and progenitor cell emergence

Article

Biochemical Society Transactions, 2022, 50(2), 703-712

 Authorship: ROSHANA THAMBYRAJAH, RUI MONTEIRO

 2022

Notch signaling in HSC emergence: when, why and how

Article

Cells, 2022, 11(3), 358

 Authorship: ROSHANA THAMBYRAJAH, ANNA BIGAS

 2022

Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE

Article

Blood, 2022,139(3), 343-356

 Authorship: MUHAMMAD ZAKI HIDAYATULLAH FADLULLAH, WEN HAO NEO, MICHAEL LIE-A-LING, ROSHANA THAMBYRAJAH, RAHIMA PATEL, RENAUD MEVEL, IRÈNE AKSOY, NAM DO KHOA, PIERRE SAVATIER, LAURA FONTENILLE, SYED MURTUZA BAKER, MAGNUS RATTRAY, VALERIE KOUSKOFF, GEORGES LACAUD

 2022

Inflammation In HSC Emergence

Article

Biomedical Journal of Scientific & Technical Research, 2021, 39(2), 31172-31174

 Authorship: ROSHANA THAMBYRAJAH

 2021

The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation

Article

Science Advances, 2020, 6(32), eabb2745

 Authorship: PEDRO VIZÁN, ARANTXA GUTIÉRREZ, ISABEL ESPEJO, MARC GARCÍA MONTOLIO, MARTIN LANGE, ANA CARRETERO, ATEFEH LAFZI, LUISA DE ANDRÉS AGUAYO, ENRIQUE BLANCO, ROSHANA THAMBYRAJAH, THOMAS GRAF, HOLGER HEYN, ANNA BIGAS, LUCIANO DI CROCE

 2020

Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation

Article

The EMBO Journal, 2020, 39(8), e104270

 Authorship: CRISTINA PORCHERI, OHAD GOLAN, FERNANDO J CALERO NIETO, ROSHANA THAMBYRAJAH, CRISTINA RUIZ HERGUIDO, XIAONAN WANG, FRANCESCA CATTO, YOLANDA GUILLÉN, ROSHANI SINHA, JESSICA GONZÁLEZ, SARAH J KINSTON, SAMANTA A . MARIANI, ANTONIO MAGLITTO, CHRIS S . VINK, ELAINE DZIERZAK, PIERRE CHARBORD, BERTIE GÖTTGENS, LLUIS ESPINOSA, DAVID SPRINZAK, ANNA BIGAS

 2020

Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta

Article

Nature Communications, 2012, 9(1), 2517

 Authorship: CHLOÉ S. BARON, LENNART KESTER, ANNA KLAUS, JEAN CHARLES BOISSET, ROSHANA THAMBYRAJAH, LAURENT YVERNOGEAU, VALÉRIE KOUSKOFF, GEORGES LACAUD, ALEXANDER VAN OUDENAARDEN, CATHERINE ROBIN

 2018

HDAC1 and HDAC2 modulate TGF-Beta signaling during endothelial-to-hematopoietic transition

Article

Stem Cell Reports, 2018, 10(4), 1369-1383

 Authorship: ROSHANA THAMBYRAJAH, MUHAMMAD Z.H. FADLULLAH, MARTIN PROFFITT, RAHIMA PATEL, SHAUN M. COWLEY, VALERIE KOUSKOFF, GEORGES LACAUD

 2018

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

Article

Blood, 2016, 128(15), 1928-1939

 Authorship: RABAB NASRALLAH, EVA M. FAST, PARHAM SOLAIMANI, KATHY KNEZEVIC, ALEXIA ELIADES, RAHIMA PATEL, ROSHANA THAMBYRAJAH, ASHWIN UNNIKRISHNAN, JULIE THOMS, DOMINIK BECK, CHRIS S. VINK, AILEEN SMITH, JASON WONG, MAIRI SHEPHERD, DAVID KENT, RAHUL ROYCHOUDHURI, FABIAN PAUL, JULIA KLIPPERT, ANNETTE HAMMES, THOMAS WILLNOW

 2016

A gene trap transposon eliminates haematopoietic expression of zebrafish Gfi1aa, but does not interfere with haematopoiesis

Article

Developmental Biology, 2016, 417(1), 25-39

 Authorship: ROSHANA THAMBYRAJAH, DENIZ UCANOK, MARYAM JALALI, YASMIN HOUGH, ROBERT NEIL WILKINSON, KATHRYN MCMAHON, CHRIS MOORE, MARTIN GERING

 2016

New insights into the regulation by RUNX1 and GFI1(s) proteins of the endothelial to hematopoietic transition generating primordial hematopoietic cells

Article

Cell Cycle, 2016, 15(16), 2108-2114

 Authorship: ROSHANA THAMBYRAJAH, RAHIMA PATEL, MILENA MAZAN, MICHAEL LIE A LING, ANDREW LILLY, ALEXIA ELIADES, SARA MENEGATTI, EVA GARCIA ALEGRIA, MAGDALENA FLORKOWSKA, KIRAN BATTA, VALERIE KOUSKOFF, GEORGES LACAUD

 2016

GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1

Article

Nature Cell Biology, 2016, 18(1), 21-32

 Authorship: ROSHANA THAMBYRAJAH, MILENA MAZAN, RAHIMA PATEL, VICTORIA MOIGNARD, MONIKA STEFANSKA, ELLI MARINOPOULOU, YAOYONG LI, CHRISTOPHE LANCRIN, THOMAS CLAPES, TARIK MÖROŸ, CATHERINE ROBIN, CRISPIN MILLER, SHAUN COWLEY, BERTHOLD GÖTTGENS, VALERIE KOUSKOFF, GEORGES LACAUD

 2016

13 results 
       

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