HP1 y prevents activation of the cGAS/STING pathway by preserving nuclear envelope and genomic integrity in colon adenocarcinoma cells

Article

International Journal of Molecular Sciences, 2023, 24(8), 7347

 Authorship: JORGE MATA-GARRIDO, LAURA FRIZZI, THIEN NGUYEN, XIANGYAN HE, YUNHUA CHANG-MARCHAND, YAO XIANG, CAROLINE REISACHER, IÑIGO CASAFONT PARRA, LAURENCE ARBIBE

 2023

Gb3/cd77 is a predictive marker and promising therapeutic target for head and neck cancer

Article

Biomedicines 2022, 10(4), 732

 Authorship: LORENA GARCÍA-HEVIA, DEBORA MUÑOZ GUERRA, IÑIGO CASAFONT PARRA, CARMELO MORALES ANGULO, VICTOR JACINTO OVEJERO GOMEZ, DAVID LOBO, MONICA LOPEZ FANARRAGA

 2022

The heterochromatin protein 1 is a regulator in RNA splicing precision deficient in ulcerative colitis

Article

Nature Communications, 2022, 13(1), 6834

 Authorship: JORGE MATA-GARRIDO, YAO XIANG, YUNHUA CHANG-MARCHAND, CAROLINE REISACHER, ELISABETH AGERON, IDA CHIARA GUERRERA, IÑIGO CASAFONT PARRA, AURELIA BRUNEAU, CLAIRE CHERBUY, XAVIER TRETON, ANNE DUMAY, ERIC OGIER-DENIS, ERIC BATSCHÉ, MICKAEL COSTALLAT, GWLADYS REVÊCHON, MARIA ERIKSSON, CHRISTIAN MUCHARDT, LAURENCE ARBIBE

 2022

Magnetic lipid nanovehicles synergize the controlled thermal release of chemotherapeutics with magnetic ablation while enabling non-invasive monitoring by MRI for melanoma theranostics

Article

Bioactive Materials, 2021, 17(8), 153-164

 Authorship: LORENA GARCÍA-HEVIA, IÑIGO CASAFONT PARRA, JESSICA OLIVEIRA, NURIA TERAN VILLAGRA, MONICA LOPEZ FANARRAGA, JUAN GALLO, MANUEL BAÑOBRE-LÓPEZ

 2021

Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA

Article

Acta Neuropathologica Communications, 2018, 6(1), 68

 Authorship: JORGE MATA GARRIDO, OLGA TAPIA MARTINEZ, IÑIGO CASAFONT PARRA, MARIA TERESA BERCIANO BLANCO, ANA CUADRADO, MIGUEL ANGEL LAFARGA COSCOJUELA

 2018

Anti-tumoral properties of bio-friendly MWCNTs

Conference object

Nanomaterials applied to Life Sciences (NALS 2017) 13th to 15th December 2017, Gijón - Spain : Book of Abstracts

 Authorship: ELOISA GONZALEZ LAVADO, NEREA ITURRIOZ RODRIGUEZ, ESPERANZA PADÍN GONZÁLEZ, FIDEL ANGEL FERNANDEZ FERNANDEZ, IÑIGO CASAFONT PARRA, JESUS ANTONIO GONZALEZ GOMEZ, MARIA DEL CARMEN PESQUERA GONZALEZ, FERNANDO GONZALEZ MARTINEZ, JUAN CARLOS VILLEGAS SORDO, RAFAEL VALIENTE BARROSO, MONICA LOPEZ FANARRAGA

 2017

Multiwalled carbon nanotubes inhibit tumor progression in a mouse model

Article

Advanced Healthcare Materials 2016, 5, 1080-1087

 Authorship: LORENA GARCÍA HEVIA, JUAN CARLOS VILLEGAS SORDO, FIDEL ANGEL FERNANDEZ FERNANDEZ, IÑIGO CASAFONT PARRA, JESUS ANTONIO GONZALEZ GOMEZ, RAFAEL VALIENTE BARROSO, MONICA LOPEZ FANARRAGA

 11/02/2016

A fast, reliable and cost-effective method to generate tumor organs for therapy screening in vivo

Article

Biomedical Physics & Engineering Express, 2(2016), 035009

 Authorship: LORENA GARCIA HEVIA, FIDEL ANGEL FERNANDEZ FERNANDEZ, IÑIGO CASAFONT PARRA, JUAN CARLOS VILLEGAS SORDO, MONICA LOPEZ FANARRAGA

 2016

Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization

Article

Acta Neuropathologica Communications, 2016, 4(41)

 Authorship: JORGE MATA GARRIDO, IÑIGO CASAFONT PARRA, OLGA TAPIA MARTINEZ, MARIA TERESA BERCIANO BLANCO, MIGUEL ANGEL LAFARGA COSCOJUELA

 2016

Dynamic behavior of the RNA polymerase II and the ubiquitin proteasome system during the neuronal DNA damage response to ionizing radiation

Article

Mol Neurobiol (2016) 53:6799-6808

 Authorship: IÑIGO CASAFONT PARRA, ANA ROSA PALANCA CUÑADO, VANESA LAFARGA, JORGE MATA GARRIDO, MARIA TERESA BERCIANO BLANCO, MIGUEL ANGEL LAFARGA COSCOJUELA

 2016

Reactive nucleolar and Cajal body responses to proteasome inhibition in sensory ganglion neurons

Article

Biochimica et Biophysica Acta. Molecular Basis of Disease, 2014, 1842(6), 848-859

 Authorship: ANA ROSA PALANCA CUÑADO, IÑIGO CASAFONT PARRA, MARIA TERESA BERCIANO BLANCO, MIGUEL ANGEL LAFARGA COSCOJUELA

 2014

Proteasome inhibition induces DNA damage and reorganizes nuclear architecture and protein synthesis machinery in sensory ganglion neurons

Article

Cellular and Molecular Life Sciences : CMLS, 2014, 71(10), 1961-1975

 Authorship: ANA ROSA PALANCA CUÑADO, IÑIGO CASAFONT PARRA, MARIA TERESA BERCIANO BLANCO, MIGUEL ANGEL LAFARGA COSCOJUELA

 2014

Contribution of genetic and epigenetic mechanisms to Wnt pathway activity in prevalent skeletal disorders

Article

Gene, 2013, 532, 165-172

 Authorship: MARIA DEL CARMEN GARCIA IBARBIA, JESÚS DELGADO-CALLE, IÑIGO CASAFONT PARRA, JAVIER VELASCO, JANA AROZAMENA GARCIA, MARIA ISABEL PEREZ NUÑEZ, MARIA ANGELES ALONSO AGUIRRE, MARIA TERESA BERCIANO BLANCO, FERNANDO ORTIZ FLORES, JOSÉ PÉREZ-CASTRILLÓN, AGUSTÍN F. FERÁNDEZ, MARIO F. FRAGA, MARIA TERESA ZARRABEITIA CIMIANO, JOSE ANTONIO RIANCHO MORAL

 2013

Nuclear speckles are involved in nuclear aggregation of PABPN1 and in the pathophysiology of oculopharyngeal muscular dystrophy

Article

Neurobiology of Disease, 2012, 46(1), 118-29

 Authorship: ROCIO BENGOECHEA IBACETA, OLGA TAPIA MARTINEZ, IÑIGO CASAFONT PARRA, JOSE ANGEL BERCIANO BLANCO, MIGUEL ANGEL LAFARGA COSCOJUELA, MARIA TERESA BERCIANO BLANCO

 2012

Sumoylation regulates nuclear localization of repressor DREAM

Article

Biochimica et Biophysica Acta - Molecular Cell Research, 2011, 1813, 1050-1058

 Authorship: MALGORZATA PALCZEWSKA, IÑIGO CASAFONT PARRA, KEDAR GHIMIRE, ANA M. ROJAS, ALFONSO VALENCIA, MIGUEL ANGEL LAFARGA COSCOJUELA, BRITT MELLSTRÖM, JOSÉ R. NARANJO

 2011

Purkinje cell degeneration in pcd mice reveals large scale chromatin reorganization and gene silencing linked to defective DNA repair

Article

Journal of Biological Chemistry VOL. 286, NO. 32, pp. 28287-28302

 Authorship: FERNANDO C. BALTANÁS, IÑIGO CASAFONT PARRA, VANESA LAFARGA, EDUARDO WERUAGA, JOSÉ R. ALONSO, MARIA TERESA BERCIANO BLANCO, MIGUEL ANGEL LAFARGA COSCOJUELA

 2011

Effect of ionizing radiation in sensory ganglion neurons: organization and dynamics of nuclear compartments of DNA damage/repair and their relationship with transcription and cell cycle

Article

Acta Neuropathologica, 2011, 122(4), 481-493

 Authorship: IÑIGO CASAFONT PARRA, ANA ROSA PALANCA CUÑADO, VANESA LAFARGA BERCIANO, MARIA TERESA BERCIANO BLANCO, MIGUEL ANGEL LAFARGA COSCOJUELA

 2011

Nucleolar disruption and cajal body disassembly are nuclear hallmarks of DNA damage-induced neurodegeneration in purkinje cells

Article

Brain Pathology, 2011, 21, 374-388

 Authorship: FERNANDO C. BALTANÁS, IÑIGO CASAFONT PARRA, EDUARDO WERUAGA, JOSÉ R. ALONSO, MARIA TERESA BERCIANO BLANCO, MIGUEL ANGEL LAFARGA COSCOJUELA

 2011

Blockade of the NFkB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo

Article

Oncogene, 2011, 30, 3537-3548

 Authorship: L. NOGUEIRA, P. RUIZ-ONTAÑÓN, ALFONSO VAZQUEZ BARQUERO, MIGUEL ANGEL LAFARGA COSCOJUELA, MARIA TERESA BERCIANO BLANCO, B. ALDAZ, LARA GRANDE GONZALEZ, IÑIGO CASAFONT PARRA, V. SEGURA, E. F. ROBLES, D. SUÁREZ, L. F. GARCÍA, J. A. MARTÍNEZ-CLIMENT, JOSE LUIS FERNANDEZ LUNA

 2011

Wnt activity, osteocytes and sclerostin expression in hip fractures and osteoarthritis

Conference object

Bone, 2011, 48, 138-139

 Authorship: J. DELGADO-CALLE, J. AROZAMENA, IÑIGO CASAFONT PARRA, RAUL JAVIER GARCIA RENEDO, ASUNCION PASCUAL CARRA, MARIA TERESA BERCIANO BLANCO, JESUS MARIA HERMOGENES GONZALEZ MACIAS, JOSE ANTONIO RIANCHO MORAL

 2011

Bortezomib induces the formation of nuclear poly(A) RNA granules enriched in Sam68 and PABPN1 in sensory ganglia neurons

Article

Neurotoxicity Research, 2010, 17, 167-178

 Authorship: IÑIGO CASAFONT PARRA, MARIA TERESA BERCIANO BLANCO, MIGUEL ANGEL LAFARGA COSCOJUELA

 2010

NANOESTRUCTURAS HÍBRIDAS BIOFUNCIONALES PARA DIAGNÓSTICO RÁPIDO, TRATAMIENTO Y SEGUIMIENTO DE LA METÁSTASIS (AYUDA FINANCIADA CONTRATO PROGRAMA GOB CANTABRIA -UC)

 Nanomedicina

 DEPARTAMENTO DE BIOLOGÍA MOLECULAR

Head: LORENA GARCIA HEVIA

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2023

Diseño de un nano-biosensor para el cribado y detección rápida del cáncer de cabeza-cuello

 Nanomedicina

 DEPARTAMENTO DE BIOLOGÍA MOLECULAR

Head: MONICA LOPEZ FANARRAGA

Typology: Competitive national public projects

Start year: 2023

DE RESIDUOS A RIQUEZA:TRANSFORMACIÓN DE SUERO LÁCTEOS EN PUNTOS CUÁNTICOS DE CARBONO PARA BIOMEDICINA Proyecto TED2021-129248B-I00 financiado por MCIN/ AEI /10.13039/501100011033 y por la Unión Europea NextGenerationEU/PRTR

 Nanomedicina

 DEPARTAMENTO DE BIOLOGÍA MOLECULAR

Head: MONICA LOPEZ FANARRAGA

Typology: Competitive national public projects

Start year: 2022

MICROESPECTROSCOPÍA RAMAN CONFOCAL COMO HERRAMIENTA DE DIAGNÓSTICO PARA EL SARS-COV-2 Y OTROS CORONAVIRUS

 Altas Presiones Y Espectroscopia

 DEPARTAMENTO DE FÍSICA APLICADA

Head: RAFAEL VALIENTE BARROSO

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2020

Engineering photoactivable cancer nanotheranostic precision tools based on carbon nanotubes

 Nanomedicina

 DEPARTAMENTO DE BIOLOGÍA MOLECULAR

Head: MONICA LOPEZ FANARRAGA

Typology: Competitive national public projects

Start year: 2020

DESARROLLO DE UN DISPOSITIVO ENDOSCÓPICO PARA EL TRATAMIENTO DE CÁNCER DE CABEZA-CUELLO MEDIANTE HIPERTERMIA FOTOINDUCIDA CON NANOPARTÍCULAS MULTIFUNCIONALES

 Nanomedicina

 DEPARTAMENTO DE BIOLOGÍA MOLECULAR

Head: MONICA LOPEZ FANARRAGA

Typology: Competitive national public projects

Start year: 2020

BIOMATERIALES FUNCIONALIZADOS PARA LIBERACIÓN CONTROLADA DE FÁRMACOS Y BIOIMAGEN A PARTIR DE NANOARCILLAS CON PROPIEDADES DE ADSORCIÓN MEJORADAS

 DEPARTAMENTO DE QUÍMICA E INGENIERÍA DE PROCESOS Y RECURSOS.

Head: ANA CARMEN PERDIGON ALLER

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2019

DETERMINACIÓN DE MUTACIONES EN BRAF MEDIANTE BIOPSIA LÍQUIDA EN PACIENTES CON SOSPECHA DE CARCINOMA PAPILAR DE TIROIDES

 DEPARTAMENTO DE CIENCIAS MÉDICAS Y QUIRÚRGICAS

Head: DIETER JOSE MORALES GARCIA

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2018

PROYECTO QUINOSOMAS PARA EL TRATAMIENTO DE LA LEISHMANIASIS COMO MODELO DE ENFERMEDAD OLVIDADA

 Nanomedicina

 DEPARTAMENTO DE BIOLOGÍA MOLECULAR

Head: MONICA LOPEZ FANARRAGA

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2017

HERRAMIENTAS NANOBIOTECNOLOGÓCIAS MODULARES DISEÑADAS PARA DETECTAR E INTERFERIR CON LA VÍA DE SEÑALIZACIÓN CLAVE DE LA FIBROSIS CARDÍACA (SODERCAN/FEDER)

 INST. DE BIOMEDICINA Y BIOTECNOLOGÍA DE CANTABRIA

Head: ANA VICTORIA VILLAR RAMOS

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2017

DISEÑO Y EVALUACION ANTITUMORAL DE NANO-DISPENSADORES MULTI-TERAPEUTICOS BASADOS EN NANOTUBOS DE CARBONO (PI16/00496) (ISCIII/FEDER)

 Nanomedicina

 DEPARTAMENTO DE BIOLOGÍA MOLECULAR

Head: MONICA LOPEZ FANARRAGA

Typology: Competitive national public projects

Start year: 2017

DISEÑO DE NANODISPENSADORES BIO-SINTÉTICOS COMO TRANSPORTADORES DE TERAPIAS AL CITOPLASMA DE MOTONEURONAS

 Nanomedicina

 DEPARTAMENTO DE ANATOMÍA Y BIOLOGÍA CELULAR

Head: JUAN CARLOS VILLEGAS SORDO

Typology: Agreements and contracts art.83, University and Competitive Chairs UC

Start year: 2017

DESARROLLO DE ANTINEOPLASICOS BASADOS EN NANOMATERIALES

 Nanomedicina

 DEPARTAMENTO DE BIOLOGÍA MOLECULAR

Head: MONICA LOPEZ FANARRAGA

Typology: Competitive national public projects

Start year: 2014

SEÑALIZACIÓN Y REPARACIÓN DEL DAÑO EN EL DNA EN NEURONAS. ORGANIZACIÓN ESTRUCTURAL, MOLECULAR, ESPACIAL Y TEMPORAL DE LOS FOCOS NUCLEARES DE LESIÓN/REPARACIÓN DEL DNA INDUCIDO (BFU2011-23983)

 DEPARTAMENTO DE ANATOMÍA Y BIOLOGÍA CELULAR

Head: MIGUEL ANGEL LAFARGA COSCOJUELA

Typology: Competitive national public projects

Start year: 2012