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28 results 
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GADD45A suppression contributes to cardiac remodeling by promoting inflammation, fibrosis and hypertrophy

Article

Cellular and Molecular Life Sciences, 2025, 82(1),189

 Authorship: ADEL ROSTAMI, XAVIER PALOMER, JAVIER PIZARRO DELGADO, LUCÍA PEÑA, MÒNICA ZAMORA, MARTA MONTORI GRAU, EMMA BARROSO, BRENDA VALENZUELA ALCARAZ, FÀTIMA CRISPI, JESÚS M. SALVADOR, RAQUEL GARCIA LOPEZ, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, MANUEL VÁZQUEZ CARRERA

 2025

A family with Meester-Loeys syndrome caused by a novel missense variant in the BGN gene

Article

International Journal of Molecular Sciences, 2025, 26(24), 12044

 Authorship: JOSE ANTONIO RIANCHO MORAL, ANA I. VEGA, ÁLVARO DEL REAL BOLT, MARIA CAROLINA SAÑUDO CAMPO, JOSÉ L. PÉREZ-CASTRILLÓN, RAQUEL GARCIA LOPEZ, NURIA PUENTE RUIZ, JUAN FRANCISCO NISTAL HERRERA, JOSÉ L. FERNÁNDEZ-LUNA

 2025

PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy

Article

Pharmacological Research, 2024, 210, 107515

 Authorship: ADEL ROSTAMI, XAVIER PALOMER, JAVIER PIZARRO-DELGADO, EMMA BARROSO, BRENDA VALENZUELA-ALCARAZ, FÁTIMA CRISPI, JUAN FRANCISCO NISTAL HERRERA, MARIA AMOR HURLE GONZALEZ, RAQUEL GARCIA LOPEZ, WALTER WAHLI, MANUEL VÁZQUEZ-CARRERA

 2024

Differential preoperative transcriptomic profiles are related to the quality of left ventricle reverse remodelling one year after valve replacement in patients with severe aortic valve stenosis

Conference object

Cardiovascular Research, 2024, 120 (Supplement 1), cvae088.012

 Authorship: MARÍA CALVO RODRÍGUEZ, CARLOS JUAREZ CRESPO, VICTOR EXPOSITO GARCIA, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, RAQUEL GARCIA LOPEZ

 2024

BMP7-based peptide agonists of BMPR1A protect the left ventricle against pathological remodeling induced by pressure overload

Article

Biomedicine & Pharmacotherapy, 2022, 149, 112910

 Authorship: ANA BELEN SALIDO MEDINA, ARITZ GIL ONGAY, VICTOR EXPOSITO GARCIA, FERNANDO MARTÍNEZ, JUAN M. REDONDO, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, RAQUEL GARCIA LOPEZ

 01/05/2022

Identification of epigenetic interactions between microRNA-30c-5p and DNA methyltransferases in neuropathic pain

Article

International Journal of Molecular Sciences, 2022, 23(22), 13994

 Authorship: RAQUEL FRANCES ROMERO, JORGE MATA GARRIDO, ROBERTO DE LA FUENTE ROYANO, MARIA CARCELEN LABRADOR, MIGUEL ANGEL LAFARGA COSCOJUELA, MARIA TERESA BERCIANO BLANCO, RAQUEL GARCIA LOPEZ, MARIA AMOR HURLE GONZALEZ, MONICA TRAMULLAS FERNANDEZ

 2022

Balance shift of activin/inhibin cytokines as part of the atrial structural remodelling of patients with aortic stenosis in atrial fibrillation

Conference object

Cardiovascular Research, 2022, 118(Supplement 1), cvac066.120

 Authorship: RAQUEL GARCIA LOPEZ, VICTOR EXPOSITO GARCIA, ANA BELEN SALIDO MEDINA, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA

 2022

Sirtuins: to be or not to be in diabetic cardiomyopathy

Article

Trends in Molecular Medicine, 2021, 27(6), 554-571

 Authorship: XAVIER PALOMER, DAVID AGUILAR-RECARTE, RAQUEL GARCIA LOPEZ, JUAN FRANCISCO NISTAL HERRERA, MANUEL VÁZQUEZ-CARRERA

 2021

Sex-specific regulation of miR-29b in the myocardium under pressure overload is associated with differential molecular, structural and functional remodeling patterns in mice and patients with aortic stenosis

Article

Cells, 2020, 9(4), 833

 Authorship: RAQUEL GARCIA LOPEZ, ANA B. SALIDO MEDINA, ARITZ GIL, DAVID MERINO, JENNY GÓMEZ, ANA VICTORIA VILLAR RAMOS, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, FRANCISCO JESUS GONZALEZ VILCHEZ

 30/03/2020

SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation

Article

Signal Transduction and Targeted Therapy, 2020, 5, 14

 Authorship: XAVIER PALOMER, JAVIER ROMÁN-AZCONA, ANA PLANAVILA, FRANCESC VILLARROYA, BRENDA VALENZUELA-ALCARAZ, FÁTIMA CRISPI, ÁLVARO SEPÚLVEDA-MARTÍNEZ, IRENE MIGUEL-ESCALADA, JORGE FERRER, JUAN FRANCISCO NISTAL HERRERA, RAQUEL GARCIA LOPEZ, MERCY M. DAVIDSON, EMMA BARROSO, MANUEL VÁZQUEZ-CARRERA

 2020

MicroRNA-30c-5p modulates neuropathic pain in rodents

Article

Science Translational Medicine, 2018, 10(453), 6299

 Authorship: MONICA TRAMULLAS FERNANDEZ, RAQUEL FRANCES ROMERO, ROBERTO DE LA FUENTE ROYANO, SARA VELATEGUI, MARIA CARCELEN LABRADOR, RAQUEL GARCIA LOPEZ, FRANCISCO JAVIER LLORCA DIAZ, MARIA AMOR HURLE GONZALEZ

 01/08/2018

Experimental modelling of cardiac pressure overload hypertrophy: modified technique for precise, reproducible, safe and easy aortic arch banding-debanding in mice

Article

Scientific Reports, 2018 , 8 (1), 3167

 Authorship: DAVID MERINO FERNANDEZ, ARITZ GIL, JENNY GÓMEZ, LUIS RUIZ, MIGUEL LLANO, RAQUEL GARCIA LOPEZ, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA

 2018

Smooth muscle enriched long noncoding RNA (SMILR) regulates cell proliferation

Article

Circulation, 2016, 133(21), 2050-2065

 Authorship: MARGARTE D. BALLANTYNE, KARINE PINEL, RACHEL DAKIN, ALEX T. VESEY, LOUISE DIVER, RUTH MACKENZIE, RAQUEL GARCIA LOPEZ, PAUL WELSH, NAVEED SATTAR, GRAHAM HAMILTON, NIKHIL JOSHI, MARC R. DWECK, JOSEPH M. MIANO, MARTIN W. MCBRIDE, DAVID E. NEWBY, ROBERT A. MCDONALD, ANDREW H. BAKER

 2016

A role for the long noncoding RNA SENCR in commitment and function of endothelial cells

Article

Molecular Therapy, 2016, 24(5), 978-990

 Authorship: MOUNIA BOULBERDAA, ELIZABETH SCOTT, MARGARET BALLANTYNE, RAQUEL GARCIA LOPEZ, BETTY DESCAMPS, GIANNI D. ANGELINI, MAIRI BRITTAN, AMANDA HUNTER, MARTIN MCBRIDE, JOHN MCCLURE, JOSEPH M. MIANO, COSTANZA EMANUELI, NICHOLAS L. MILLS, JOANNE C. MOUNTFORD, ANDREW H. BAKER

 2016

BMP-7 attenuates left ventricular remodelling under pressure overload and facilitates reverse remodelling and functional recovery

Article

Cardiovascular Research, 2016, 110(3), 331-345

 Authorship: DAVID MERINO FERNANDEZ, ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MONICA TRAMULLAS FERNANDEZ, LUIS RUIZ, CATALINA RIBAS, SOFÍA CABEZUDO, JUAN FRANCISCO NISTAL HERRERA, MARIA AMOR HURLE GONZALEZ

 01/04/2016

Extracellular heat shock protein 90 binding to TGFbeta receptor I participates in TGFbeta-mediated collagen production in myocardial fibroblasts

Article

Cellular Signalling, 2016, 28(10), 1563-1579

 Authorship: RAQUEL GARCIA LOPEZ, DAVID MERINO FERNANDEZ, JENNY M GÓMEZ, JUAN FRANCISCO NISTAL HERRERA, MARIA AMOR HURLE GONZALEZ, AITZIBER L. CORTAJARENA, ANA VICTORIA VILLAR RAMOS

 2016

p-SMAD2/3 and DICER promote pre-miR-21 processing during pressure overload-associated myocardial remodeling

Article

Biochimica et Biophysica Acta. Molecular Basis of Disease, 2015, 1852(7), 1520-30

 Authorship: RAQUEL GARCIA LOPEZ, JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO FERNANDEZ, NATHAN L PRICE, CARLOS FERNANDEZ HERNANDO, JAVIER BEAUMONT, ARANTXA GONZÁLEZ, MARIA AMOR HURLE GONZALEZ, ANA VICTORIA VILLAR RAMOS

 2015

Desequilibrio de señalización BMP7 frente a TGFB en el remodelado del ventrículo izquierdo por sobrecarga de presión: estudio traslacional

Conference object

Revista Española de Cardiología, 2015, 68(Supl.1), 386

 Authorship: JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO GARCÍA, ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MONICA TRAMULLAS FERNANDEZ, LUIS RUIZ GUERRERO, CATALINA RIBAS NÚÑEZ, MARIA AMOR HURLE GONZALEZ

 2015

Influencia de la proteína de choque térmico 90 en la expresión de mediadores y dianas profibróticas del factor de crecimiento transformante beta en el corazón sometido a sobrecarga de presión

Conference object

Revista Española de Cardiología, 2015, 68(Supl.1), 1097

 Authorship: RAQUEL GARCIA LOPEZ, JENNY GÓMEZ, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA, ANA VICTORIA VILLAR RAMOS

 2015

The normal balance between antifibrotic Bmp7 and profibrotic Tgfâ signaling is lost on the pressure overloadinduced LV remodeling and can be modified favorably. A translational study

Conference object

Circulation, 2015, 132, A14298

 Authorship: JUAN FRANCISCO NISTAL HERRERA, DAVID MERINO FERNANDEZ, ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MONICA TRAMULLAS FERNANDEZ, LUIS RUIZ GUERRERO, CATALINA RIBAS, MARIA AMOR HURLE GONZALEZ

 2015

Regulación por TGF-B del procesamiento de microRNA-21 por DICER y su papel fisiopatológico en el remodelado VI por sobrecarga de presión en el animal de experimentación y en la clínica

Conference object

Revista Española de Cardiología, 2014, 67( Supl.1), 868

 Authorship: JUAN FRANCISCO NISTAL HERRERA, RAQUEL GARCIA LOPEZ, DAVID MERINO FERNANDEZ, MARIA AMOR HURLE GONZALEZ, ANA VICTORIA VILLAR RAMOS

 2014

Circulating levels of miR-133a predict the regression potential of left ventricular hypertrophy after valve replacement surgery in patients with aortic stenosis

Article

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2013, 2(4), e000211

 Authorship: RAQUEL GARCIA LOPEZ, ANA VICTORIA VILLAR RAMOS, MANUEL COBO, MIGUEL LLANO, RAFAEL MARTÍN-DURÁN, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA

 2013

BAMBI (BMP and activin membrane-bound inhibitor) protects the murine heart from pressure-overload biomechanical stress by restraining TGF-ß signaling

Article

Biochimica et Biophysica Acta. Molecular Basis of Disease, 2013, 1832(2), 323-35

 Authorship: ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, MIGUEL LLANO, MANUEL COBO, DAVID MERINO, AQUILINO LANTERO, MONICA TRAMULLAS FERNANDEZ, JUAN MARIO HURLE GONZALEZ, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA

 2013

Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients

Article

International Journal of Cardiology, 2013, 167(6), 2875-81

 Authorship: ANA VICTORIA VILLAR RAMOS, RAQUEL GARCIA LOPEZ, DAVID MERINO, MIGUEL LLANO, MANUEL COBO, CECILIA MONTALVO, RAFAEL MARTÍN-DURÁN, MARIA AMOR HURLE GONZALEZ, JUAN FRANCISCO NISTAL HERRERA

 2013

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