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 Detalle_Publicacion

Characterization of optical coherence tomography images for colon lesion differentiation under deep learning

Abstract: (1) Background: Clinicians demand new tools for early diagnosis and improved detection of colon lesions that are vital for patient prognosis. Optical coherence tomography (OCT) allows microscopical inspection of tissue and might serve as an optical biopsy method that could lead to in-situ diagnosis and treatment decisions; (2) Methods: A database of murine (rat) healthy, hyperplastic and neoplastic colonic samples with more than 94,000 images was acquired. A methodology that includes a data augmentation processing strategy and a deep learning model for automatic classification (benign vs. malignant) of OCT images is presented and validated over this dataset. Comparative evaluation is performed both over individual B-scan images and C-scan volumes; (3) Results: A model was trained and evaluated with the proposed methodology using six different data splits to present statistically significant results. Considering this, 0.9695 (_0.0141) sensitivity and 0.8094 (_0.1524) specificity were obtained when diagnosis was performed over B-scan images. On the other hand, 0.9821 (_0.0197) sensitivity and 0.7865 (_0.205) specificity were achieved when diagnosis was made considering all the images in the whole C-scan volume; (4) Conclusions: The proposed methodology based on deep learning showed great potential for the automatic characterization of colon polyps and future development of the optical biopsy paradigm.

Otras publicaciones de la misma revista o congreso con autores/as de la Universidad de Cantabria

 Autoría: Saratxaga C.L., Bote J., Ortega-Morán J.F., Picón A., Terradillos E., del Río N.A., Andraka N., Garrote E., Conde O.M.,

 Fuente: Applied Sciences, 2021, 11(7), 3119

Editorial: MDPI

 Fecha de publicación: 01/04/2021

Nº de páginas: 19

Tipo de publicación: Artículo de Revista

 DOI: 10.3390/app11073119

ISSN: 2076-3417

Autores/as

LÓPEZ SARATXAGA, CRISTINA

BOTE CHACON, JORGE

ORTEGA MORÁN, JUAN FRANCISCO

PICÓN RUIZ, ARTZAI

TERRADILLOS FERNÁNDEZ, ELENA

ARBIDE DEL RÍO, NAGORE

ANDRAKA RUEDA, NAGORE

ESTIBALIZ GARROTE CONTRERAS