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Abstract: Ketamine's pharmacological profile makes it an interesting and useful drug to challenge treatment-resistant-depression (TRD). Emerging adverse events associated with single-slow-sub-anaesthetic doses for the treatment of depression are common, although generally transient and self-limited. Nevertheless, data on the safety of this practice are scarce. Thus, it seems timely before ketamine is used for clinical treatment of depression to recommend careful monitoring and reporting of all potential adverse events related to ketamine administration. Here, we describe a case of apnea during slow sub-anaesthetic infusion of intravenous ketamine for the treatment of resistant depression. As far as we are concerned, this is an uncommon, previously unreported, and potentially severe adverse event that clinicians should be aware of, and specific management measures should be implemented.
Fuente: Therapeutic Advances in Psychopharmacology. January 2020, Vol. 10: 1-7
Editorial: SAGE journals
Fecha de publicación: 01/01/2020
Tipo de publicación: Artículo de Revista
DOI: 10.1177/2045125320981498
ISSN: 2045-1253,2045-1261
Url de la publicación: https://journals.sagepub.com/doi/10.1177/2045125320981498
Consultar en UCrea Leer publicación
MARCOS GOMEZ REVUELTA
FERNÁNDEZ RODRÍGUEZ, MARÍA
BOADA ANTÓN, LAURA
JAVIER VAZQUEZ BOURGON
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