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 Detalle_Publicacion

Apnea during slow sub-anaesthetic infusion of intravenous ketamine for treatment-resistant depression

Abstract: Ketamine's pharmacological profile makes it an interesting and useful drug to challenge treatment-resistant-depression (TRD). Emerging adverse events associated with single-slow-sub-anaesthetic doses for the treatment of depression are common, although generally transient and self-limited. Nevertheless, data on the safety of this practice are scarce. Thus, it seems timely before ketamine is used for clinical treatment of depression to recommend careful monitoring and reporting of all potential adverse events related to ketamine administration. Here, we describe a case of apnea during slow sub-anaesthetic infusion of intravenous ketamine for the treatment of resistant depression. As far as we are concerned, this is an uncommon, previously unreported, and potentially severe adverse event that clinicians should be aware of, and specific management measures should be implemented.

 Fuente: Therapeutic Advances in Psychopharmacology. January 2020, Vol. 10: 1-7

Editorial: SAGE journals

 Fecha de publicación: 01/01/2020

Tipo de publicación: Artículo de Revista

 DOI: 10.1177/2045125320981498

ISSN: 2045-1253,2045-1261

Url de la publicación: https://journals.sagepub.com/doi/10.1177/2045125320981498

Autores/as

MARCOS GOMEZ REVUELTA

FERNÁNDEZ RODRÍGUEZ, MARÍA

BOADA ANTÓN, LAURA