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Abstract: Background. The aim of the current study was to examine the heterogeneity of functional
outcomes in first episode psychosis (FEP) patients and related clinical, neurocognitive and
sociodemographic factors using a cluster analytic approach.
Method. A large sample of FEP patients (N = 209) was functionally reassessed 10 years after
the first contact with an early intervention service. Multiple baseline, 3-year and 10-year follow-
up variables were explored.
Results. The cluster analysis emphasized the existence of six independent clusters of functioning:
one cluster was normal overall (42.16%), two clusters showed moderate interpersonal
(9.63%) or instrumental (12.65%) deficits, two clusters showed more severe interpersonal
(12.05%) or interpersonal and instrumental (13.85%) deficits and there was a significantly
overall impaired cluster (9.63%). Cluster comparisons showed that several baseline and follow-
up factors were differentially involved in functional outcomes.
Conclusions. The current study demonstrated that distinct clusters of functioning in FEP
patients can be identified. The fact that a variety of profiles was observed contributes to a
better understanding of the nature of the heterogeneity characterizing FEP patients and has
clinical implications for developing individualized treatment plans.
Fuente: Psychological Medicine, 51(2), 264-277
Editorial: Cambridge University Press
Fecha de publicación: 01/01/2021
Nº de páginas: 14
Tipo de publicación: Artículo de Revista
AYESA ARRIOLA, ROSA
ORTÍZ GARCÍA DE LA FOZ, VÍCTOR
MARTÍNEZ GARCÍA, OBDULIA
SETIÉN SUERO, ESTHER
RAMÍREZ, MARÍA LUZ
PAULA SUAREZ PINILLA
MAYORAL VAN SON, JAQUELINE
JAVIER VAZQUEZ BOURGON
JUNCAL RUIZ, MARÍA
GÓMEZ REVUELTA, MARCOS
TORDESILAS GUTIÉRREZ, DIANA
BENEDICTO CRESPO FACORRO