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 Detalle_Publicacion

Infective endocarditis in patients with heart transplantation

Abstract: Background: The incidence of nosocomial and health care-related infective endocarditis (IE) is increasing. Heart transplantation (HT) implies immunosuppression and frequent health care contact. Our aim was to describe the current profile and prognosis of IE in HT recipients. Methods: Multicenter retrospective registry-based study in Spain and France that included cases between 2008 and 2019. Results: During the study period, 8305 HT were performed in Spain and France. We identified 18 IE cases (rate 0.2%). Median age was 57 years; 12 were men (67%). Valve involvement did not have a predominant location and three patients (16.7%) had atrial or ventricular vegetations without valve involvement. The median ageadjusted Charlson index was 4 (interquartile range 3?5). Eleven IE cases (61%) were nosocomial/health care related. Median time (range) between HT and development of IE was 43 months (interquartile range 6?104). The major pathogens were Staphylococcus sp. (n = 8, 44%), Enterococcus sp. (n = 4, 22%), and Aspergillus sp. (n = 3, 17%). Although eight patients (44%) had a surgical indication, it was only performed in three cases (17%). Three patients (17%) died during the first IE hospital admission. Conclusions: IE in HT recipients has specific characteristics. Valve involvement does not have a predominant location and non-valvular involvement is common. Three fifths have a nosocomial/health care-related origin. The major pathogens were staphylococci (44%), enterococci (22%), and Aspergillus (17%). In-hospital mortality was 17%.

 Fuente: International Journal of Cardiology 328 (2021) 158-162

Editorial: Elsevier

 Fecha de publicación: 01/04/2021

Nº de páginas: 5

Tipo de publicación: Artículo de Revista

 DOI: doi.org/10.1016/j.ijcard.2020.12.018

ISSN: 0167-5273,1874-1754

Url de la publicación: https://doi.org/10.1016/j.ijcard.2020.12.018

Autores/as

MARTÍNEZ-SELLÉS, MANUEL

TATTEVIN, PIERRE

VALERIO-MINERO, MARICELA

ALARCÓN, ARÍSTIDES DE

MIRABET-PÉREZ, SÒNIA

LAVIE-BADIE, YOAN

AMBROSI, PIERRE

CHABANNE, CÉLINE

DUVAL, XAVIER

LECOMTE, RAPHAËL

LÓPEZ-VILELLA, RAQUEL

URIBARRI, AITOR

VINUESA, DAVID

MUÑOZ, PATRICIA