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Iterative Otsu's method for OCT improved delineation in the aorta wall

Abstract: Degradation of human ascending thoracic aorta has been visualized with Optical Coherence Tomography (OCT). OCT images of the vessel wall exhibit structural degradation in the media layer of the artery, being this disorder the final trigger of the pathology. The degeneration in the vessel wall appears as low-reflectivity areas due to different optical properties of acidic polysaccharides and mucopolysaccharides in contrast with typical ordered structure of smooth muscle cells, elastin and collagen fibers. An OCT dimension indicator of wall degradation can be generated upon the spatial quantification of the extension of degraded areas in a similar way as conventional histopathology. This proposed OCT marker can offer in the future a real-time clinical perception of the vessel status to help cardiovascular surgeons in vessel repair interventions. However, the delineation of degraded areas on the B-scan image from OCT is sometimes difficult due to presence of speckle noise, variable signal to noise ratio (SNR) conditions on the measurement process, etc. Degraded areas can be delimited by basic thresholding techniques taking advantage of disorders evidences in B-scan images, but this delineation is not optimum in the aorta samples and requires complex additional processing stages. This work proposes an optimized delineation of degraded areas within the aorta wall, robust to noisy environments, based on the iterative application of Otsu’s thresholding method. Results improve the delineation of wall anomalies compared with the simple application of the algorithm. Achievements could be also transferred to other clinical scenarios: carotid arteries, aorto-iliac or ilio-femoral sections, intracranial, etc.

Otras comunicaciones del congreso o articulos relacionados con autores/as de la Universidad de Cantabria

 Autoría: Alonso D., Real E., Val-Bernal J., Revuelta J., Pontón A., Calvo Díez M., Mayorga M., López-Higuera J., Conde O.,

 Congreso: European Conference on Biomedical Optics, ECBO (2015 : Munich, Alemania)

Editorial: The Optical Society (OSA) - SPIE Society of Photo-Optical Instrumentation Engineers

 Año de publicación: 2015

Nº de páginas: 6

Tipo de publicación: Comunicación a Congreso

DOI: 10.1117/12.2183720

ISSN: 0277-786X,1996-756X

Proyecto español: FIS2010-19860 ; TEC2013-47264-C2-1-R

Url de la publicación: https://doi.org/10.1117/12.2183720

Autores/as

DANIEL ALONSO SARO

EUSEBIO REAL PEÑA

JOSE FERNANDO VAL BERNAL

JOSE MANUEL REVUELTA SOBA

ALEJANDRO PONTON CORTINA

MARTA CALVO DIEZ

MARTA M. MAYORGA FERNANDEZ