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Abstract: Objective To analyze the impact of a speciic thoracic
donor-treatment protocol (including restrictive luid balance)
on kidney donation and on kidney graft survival.
Methods A cohort study. Lung Donors and kidney recipients
from 2003 to 2008 were the pre-protocol cohort, and
those from 2009 to 2013 were the protocol cohort. The
main outcome variables were graft survival and rate of kidney
Results Kidney donation rates were similar in both periods
(86.2 vs. 86.2 %; p > 0.05). Both donors and kidney
recipients were older and with more comorbidities in the
protocol group and this is the reason there were more cases of delayed graft function (diferences not statistically signiicant)
and with higher sequential creatinine levels of kidney
recipients during the protocol period. However, graft
survival was similar in both groups. The probability of
graft survival 5 years after transplantation was 0.75 (95 %
conidence interval 0.65?0.85) in the pre-protocol cohort
and 0.81 (0.70?0.92) in the protocol cohort.
Conclusions Speciic treatment for multi-organ donors
including restrictive luid balance does not afect kidney
donation or kidney graft loss, and has no impact on longterm
viability. Hemodynamics must be closely monitored
by medical personnel with speciic training.
Fuente: Journal of Nephrology. 2017; vol. 30: p. 869-875
Año de publicación: 2017
Nº de páginas: 7
Tipo de publicación: Artículo de Revista
MARIA ANGELES BALLESTEROS SANZ
DUERTO ÁLVAREZ, JORGE
LUIS MARTIN PENAGOS
EMILIO RODRIGO CALABIA
MANUEL ANTONIO ARIAS RODRIGUEZ
EDUARDO MIÑAMBRES GARCIA