Measurement of health-related quality of life (HRQoL) is important for a chronic disease,
such as dementia, which impairs the quality of life of affected patients in addition to their
length of life. This is important in the context of economic evaluations when interventions do
not (only) affect HRQoL and these other factors also affect overall quality of life.
To validate the Spanish translation of the ICECAP-O's capability to measure Health-related
quality of life in elderly with dementia who live in nursing homes.
Cross-sectional study. For 217 residents living in 8 Spanish nursing homes, questionnaires
were completed by nursing professionals serving as proxy respondents. We analyzed the
internal consistency and other psychometric properties. We investigated the convergent
validity of the ICECAP-O with other HRQoL instruments, the EQ-5D extended with a cognitive
dimension (EQ-5D+C), the Alzheimer's Disease Related Quality of Life (ADRQL) measures,
and the Barthel Index measure of activities of daily living (ADL).
The ICECAP-O presents satisfactory internal consistency (alpha 0.820). The factorial analysis
indicated a structure of five principal dimensions that explain 66.57% of the total variance.
Convergent validity between the ICECAP-O, EQ-5D+C, ADRQL, and Barthel Index
scores was moderate to good (with correlations of 0.62, 0.61, and 0.68, respectively), but
differed between dimensions of the instruments. Discriminant validity was confirmed by finding
differences in ICECAP-O scores between subgroups based on ADL scores (0.70 low, 0.59 medium, and 0.39 high level care), dementia severity (0.72 mild, 0.63 medium, and
0.50 severe), and ages (0.59 below 75 years and 0.84 above 75 years).
This study presented the first use of a Spanish version of the ICECAP-O. The results indicate
that the ICECAP-O appears to be a reliable Health-related quality of life measurement
instrument showing good convergent and discriminant validity for people with dementia.
Fuente: PLoS ONE 12(1): e0169354
Editorial: Public Library of Science
Año de publicación: 2017
Nº de páginas: 13
Tipo de publicación: Artículo de Revista
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CARMEN MARIA SARABIA COBO
PAULA PARAS BRAVO
FRANCISCO JOSE AMO SETIEN
ANA ROSA ALCONERO CAMARERO
MARIA SAENZ JALON
BLANCA TORRES MANRIQUE
RAQUEL SARABIA LAVIN
ANGELA FERNANDEZ RODRIGUEZ
TAMARA SILIO GARCIA
ROSARIO FERNANDEZ PEÑA
MARIA PAZ ZULUETA
MIGUEL SANTIBAÑEZ MARGÜELLO