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Abstract: Kawasaki disease (KD) is a vasculitis of unelucidated pathogenesis that usually occurs in paediatric patients. In this study
we analyse the temporal pattern and geographical distribution of the disease in Spain, and its relationship with atmospheric
circulation patterns. We performed a retrospective study in which we collected all hospital admissions due to KD in the
country between 2005 and 2015 and explored their relationship with demographic and geographical characteristics. Moreover,
we calculated daily surface atmospheric patterns over Spain to study the relationship between weather types (WT) and KD
Admissions. The average admission rate for KD in the paediatric population was 3.90 per 100,000, with a male to female ratio
of 1.56:1. The highest rate of admissions was found in the 0?4-year-old group, with an incidence of 11.7 cases per 100,000.
Admissions followed an annual cyclic pattern with a peak of incidence in January (p = 0.022) and a nadir in September.
There was an upwards trend in the number of KD admissions in male sex during the study period (p = 0.004). However, there
were marked geographical differences in the incidence rate. Finally, the analysis of the relationship between the WT and
the number of admissions by KD revealed no statistically significant association. KD admissions follow a peculiar seasonal
and spatial distribution, that suggest the involvement of environmental factors in the disease; however, the absence of an
association with WT should be interpreted with caution and regional studies should be done to explore this relationship.
Fuente: Rheumatol Int. 2018 Jul;38(7):1259-1266
Editorial: Springer international
Año de publicación: 2018
Nº de páginas: 8
Tipo de publicación: Artículo de Revista
Url de la publicación: https://doi.org/10.1007/s00296-018-4066-5
LEYRE RIANCHO ZARRABEITIA
DOMINGO FERNANDO RASILLA ALVAREZ
FERNÁNDEZ ARROYABE, PABLO
ANA SANTURTUN ZARRABEITIA