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Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring in clinical practice: the spanish cohort of the COMORA study

Abstract: OBJECTIVES: To describe the prevalence of comorbidities in patients with RA in Spain and discuss their management and implications using data from the Spanish cohort of the multinational study on COMOrbidities in Rheumatoid Arthritis (COMORA). METHODS: This is a national sub-analysis of the COMORA study. We studied the demographics and disease characteristics of 200 adults patients diagnosed with RA (1987 ACR), and routine practices for screening and preventing the following selected comorbidities: cardiovascular, infections, cancer, gastrointestinal, pulmonary, osteoporosis and depression. RESULTS: Patients had a mean age of 58 years and a mean RA duration of 10 years. Mean DAS28 score was 3.3 and approximately 25% of patients were in remission (DAS28 <2.6). Forty-four (22%) patients had ?1 comorbidity, the most frequent being depression (27%) and obesity (26%). A history of myocardial infarction or stroke was observed in 5% and 1% of patients, respectively, and any solid tumor in 6%. Having a Framingham Risk Score >20% (51%), hypercholesterolemia (46%) or hypertension (41%) and smoking (25%) were the most common CV risk factors. For prostate, colon and skin cancers, only 9%, 10% and 18% of patients, respectively, were optimally monitored. Infections were also inadequately managed, with 7% and 17% of patients vaccinated against influenza and pneumococcal, respectively, as was osteoporosis, with 47% of patients supplemented with vitamin D and 56% with a bone densitometry performed. CONCLUSIONS: In Spain, the prevalence of comorbidities and CV risk factors in RA patients with established and advanced disease is relatively high, and their management in clinical daily practice remains suboptimal.

Otras publicaciones de la misma revista o congreso con autores/as de la Universidad de Cantabria

 Fuente: Reumatol Clin. 2019 Mar - Apr;15(2):102-108

Editorial: Elsevier España

 Año de publicación: 2019

Nº de páginas: 7

Tipo de publicación: Artículo de Revista

 DOI: 10.1016/j.reuma.2017.06.002

ISSN: 1699-258X,1885-1398,1886-3604

Url de la publicación: https://dx.doi.org/10.1016/j.reuma.2017.06.002

Autores/as

BALSA, ALEJANDRO

LOJO OLIVEIRA, LETICIA

ALPERI LÓPEZ, MERCEDES

GARCÍA MANRIQUE, MARÍA

ORDÓÑEZ CAÑIZARES, CARMEN

PÉREZ, LORENA

RUIZ ESQUIDE, VIRGINIA

ALFONSO FERNANDO CORRALES MARTINEZ

NARVÁEZ, JAVIER

REY REY, JOSÉ

RODRÍGUEZ LOZANO, CARLOS

OJEDA, SOLEDAD

MUÑOZ FERNÁNDEZ, SANTIAGO

NOLLA, JOAN M.

GARCÍA TORRÓN, JOSÉ

GAMERO, FERNANDO

GARCÍA VICUÑA, ROSARIO

HERNÁNDEZ CRUZ, BLANCA