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To describe the prevalence of comorbidities in patients with RA in Spain and discuss their management and implications using data from the Spanish cohort of the multinational study on COMOrbidities in Rheumatoid Arthritis (COMORA).
This is a national sub-analysis of the COMORA study. We studied the demographics and disease characteristics of 200 adults patients diagnosed with RA (1987 ACR), and routine practices for screening and preventing the following selected comorbidities: cardiovascular, infections, cancer, gastrointestinal, pulmonary, osteoporosis and depression.
Patients had a mean age of 58 years and a mean RA duration of 10 years. Mean DAS28 score was 3.3 and approximately 25% of patients were in remission (DAS28 <2.6). Forty-four (22%) patients had ?1 comorbidity, the most frequent being depression (27%) and obesity (26%). A history of myocardial infarction or stroke was observed in 5% and 1% of patients, respectively, and any solid tumor in 6%. Having a Framingham Risk Score >20% (51%), hypercholesterolemia (46%) or hypertension (41%) and smoking (25%) were the most common CV risk factors. For prostate, colon and skin cancers, only 9%, 10% and 18% of patients, respectively, were optimally monitored. Infections were also inadequately managed, with 7% and 17% of patients vaccinated against influenza and pneumococcal, respectively, as was osteoporosis, with 47% of patients supplemented with vitamin D and 56% with a bone densitometry performed.
In Spain, the prevalence of comorbidities and CV risk factors in RA patients with established and advanced disease is relatively high, and their management in clinical daily practice remains suboptimal.
Fuente: Reumatol Clin. 2019 Mar - Apr;15(2):102-108
Editorial: Elsevier España
Año de publicación: 2019
Nº de páginas: 7
Tipo de publicación: Artículo de Revista
Url de la publicación: https://dx.doi.org/10.1016/j.reuma.2017.06.002
LOJO OLIVEIRA, LETICIA
ALPERI LÓPEZ, MERCEDES
GARCÍA MANRIQUE, MARÍA
ORDÓÑEZ CAÑIZARES, CARMEN
RUIZ ESQUIDE, VIRGINIA
ALFONSO FERNANDO CORRALES MARTINEZ
REY REY, JOSÉ
RODRÍGUEZ LOZANO, CARLOS
MUÑOZ FERNÁNDEZ, SANTIAGO
NOLLA, JOAN M.
GARCÍA TORRÓN, JOSÉ
GARCÍA VICUÑA, ROSARIO
HERNÁNDEZ CRUZ, BLANCA
MIGUEL ANGEL GONZALEZ-GAY MANTECON