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Carotid ultrasound is useful for the cardiovascular risk stratification in patients with hidradenitis suppurativa

Abstract: INTRODUCTION: Hidradenitis suppurativa (HS) is a chronic inflammatory cutaneous disease which has been associated with an increased risk of adverse cardiovascular (CV) outcomes. Adequate stratification of the CV risk is an issue of major importance in patients with HS. To analyze the usefulness of carotid ultrasound (US) assessment for the CV disease risk stratification compared with a traditional score, the Framingham risk score (FRS), in a series of patients with HS. METHODS: Cross-sectional study of 60 patients with HS without history of CV events, diabetes mellitus or chronic kidney disease. Information on CV risk factors was collected and the FRS was calculated. Thus, the patients were classified into low, intermediate and high-CV disease risk categories based on FRS. Carotid US was performed in all participants, and the presence of atherosclerotic plaques was considered as a marker of high CV risk. RESULTS: HS patients had a mean age of 45.1±10.2 years, and 55% were female. The median FRS was 5.7 (IQR: 3.1-14.7). Twenty-four (40%) of the patients were classified into the low risk group, 28 (46.7%) in the intermediate risk group, and 8 (13.3%) into the FRS-high risk category. Noteworthy, carotid US revealed that about one-third of the patients (17/52; 32.6%) in the FRS-based low and intermediate risk categories had carotid plaques, and, therefore, they were reclassified into a high-risk category. CONCLUSION: CV risk in HS patients may be underestimated by using the FRS. Carotid US may be useful to improve the CV risk stratification of patients with HS.

Otras publicaciones de la misma revista o congreso con autores/as de la Universidad de Cantabria

 Fuente: PLoS One. 2018 Jan 4;13(1):e0190568

Editorial: Public Library of Science

 Año de publicación: 2018

Nº de páginas: 11

Tipo de publicación: Artículo de Revista

 DOI: 10.1371/journal.pone.0190568

ISSN: 1932-6203

Url de la publicación: https://doi.org/10.1371/journal. pone.0190568

Autores/as

MATA, CRISTINA

LÓPEZ ESCOBAR, MARÍA

ALFONSO FERNANDO CORRALES MARTINEZ

LÓPEZ MEJÍAS, RAQUEL

JAVIER RUEDA GOTOR

MARIA CARMEN GONZALEZ VELA

RICARDO BLANCO ALONSO