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Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies

Abstract: Effective cancer treatment has been precluded by the presence of various forms of intratumoral complexity that drive treatment resistance and metastasis. Recent single-cell sequencing technologies are significantly facilitating the characterization of tumor internal architecture during disease progression. New applications and advances occurring at a fast pace predict an imminent broad application of these technologies in many research areas. As occurred with next-generation sequencing (NGS) technologies, once applied to clinical samples across tumor types, single-cell sequencing technologies could trigger an exponential increase in knowledge of the molecular pathways involved in cancer progression and contribute to the improvement of cancer treatment.

 Fuente: Trends Cancer . 2020 Jan;6(1):13-19

Editorial: Cell Press

 Año de publicación: 2020

Nº de páginas: 7

Tipo de publicación: Artículo de Revista

 DOI: 10.1016/j.trecan.2019.11.010

ISSN: 2405-8033,2405-8025

Url de la publicación: https://doi.org/10.1016/j.trecan.2019.11.010