Abstract: This paper analyzes the notch effect on the fracture behavior of two biomaterials (a brittle bone cement and a ductile dental material) under mode I loading. U-notched Brazilian disk (UNBD) specimens of both materials were tested under remote compression, determining the corresponding fracture loads and load-displacement curves. Additionally, cracked rectangular and semicircular bend (SCB) specimens were tested under symmetric three-point bending in order to determine the fracture toughness of the two materials. Then, fracture loads were derived theoretically by applying the maximum tangential stress (MTS) and the mean stress (MS) criteria. Due to the brittle linear elastic behavior of the bone cement material, the MTS and MS criteria were directly applied to this material; however, given the significant nonlinear behavior of the dental material, the two fracture criteria were combined with the Equivalent Material Concept (EMC) for the fracture analyses of the dental material specimens. The results reveal a very good accuracy of both the MTS and the MS criteria for the fracture analysis of bone cement notched specimens. In the case of the dental material, very good results are also obtained when combining the MTS and the MS criteria with the EMC. The proposed approach can be useful for the fracture analysis of a wide range of biopolymers, from brittle to ductile behavior

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