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Quality of life in a cohort of 1078 women diagnosed with breast cancer in Spain: 7-year follow-up results in the MCC-Spain study

Abstract: ABSTRACT: Breast cancer is the most frequent cause of tumors and net survival is increasing. Achieving a higher survival probability reinforces the importance of studying health-related quality of life (HR-QoL). The main aim of this work is to test the relationship between different sociodemographic, clinical and tumor-intrinsic characteristics, and treatment received with HR-QoL measured using SF-12 and the FACT/NCCN (National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy) Breast Symptom Index (FBSI). Women with breast cancer recruited between 2008 and 2013 and followed-up until 2017?2018 in a prospective cohort answered two HR-QoL surveys: the SF-12 and FBSI. The scores obtained were related to woman and tumor characteristics using linear regression models. The telephone survey was answered by 1078 women out of 1685 with medical record follow-up (64%). Increases in all three HR-QoL scores were associated with higher educational level. The score differences between women with university qualifications and women with no schooling were 5.43 for PCS-12, 6.13 for MCS-12 and 4.29 for FBSI. Histological grade at diagnosis and recurrence in the follow-up displayed a significant association with mental and physical HR-QoL, respectively. First-line treatment received was not associated with HR-QoL scores. On the other hand, most tumor characteristics were not associated with HR-QoL. As breast cancer survival is improving, further studies are needed to ascertain if these differences still hold in the long run.

Otras publicaciones de la misma revista o congreso con autores/as de la Universidad de Cantabria

 Autoría: Alonso-Molero J., Dierssen-Sotos T., Gomez-Acebo I., Baz N.F.d.L., Guevara M., Amiano P., Castaño-Vinyals G., Fernandez-Villa T., Moreno V., Bayo J., Molina-Barceloa A., Fernández-Ortíz M., Suarez-Calleja C., Marcos-Gragera R., Castells X., Gil-Majuelo L., Ardanaz E., Pérez-Gómez B., Kogevinas M., Pollán M., Llorca J.,

 Fuente: International journal of environmental research and public health 2020, 17(22), 8411

Editorial: MDPI

 Año de publicación: 2020

Nº de páginas: 16

Tipo de publicación: Artículo de Revista

 DOI: 10.3390/ijerph17228411

ISSN: 1661-7827,1660-4601

Url de la publicación: https://doi.org/10.3390/ijerph17228411

Autores/as

FERNANDEZ DE LARREA BAZ, NEREA

GUEVARA, MARCELA

AMIANO, PILAR

CASTAÑO-VINYALS, GEMMA

FERNANDEZ-VILLA, TANIA

MORENO, VICTOR

BAYO, JUAN

MOLINA-BARCELÓ, ANA

MARIA FERNANDEZ ORTIZ

SUAREZ-CALLEJA, CLAUDIA

MARCOS-GRAGERA, RAFAEL

CASTELLS, XAVIER

GIL-MAJUELO, LEIRE

ARDANAZ, EVA

PÉREZ-GÓMEZ, BEATRIZ

KOGEVINAS, MANOLIS