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Abstract: The simplicity and low cost of rapid point-of-care tests greatly facilitate large-scale population testing, which can contribute to controlling the spread of the COVID-19 virus. We evaluated the applicability of a self-testing strategy for SARS-CoV2 in a population-based, cross-sectional study in Cantabria, Spain, between April and May 2020. For the self-testing strategy, participants received the necessary material for the self-collection of blood and performance of a rapid antibody test using lateral flow immunoassay at home without the supervision of healthcare personnel. A total of 1,022 participants were enrolled. Most participants correctly performed the COVID-19 self-test the first time (91.3% [95% CI 89.4-92.9]). Only a minority of the participants (0.7%) needed the help of healthcare personnel, while 6.9% required a second kit delivery, for a total valid test result in 96.9% of the participants. Incorrect use of the self-test was not associated with the educational level, age over 65, or housing area. Prevalence of IgG antibodies against SARS-CoV2 for subjects with a valid rapid test result was 3.1% (95% CI 2.2-4.4), similar to the seroprevalence result obtained using a conventional approach carried out by healthcare professionals. In conclusion, COVID-19 self-testing should be considered as a screening tool.
Fuente: Sci Rep . 2021 May 10;11(1):9819
Editorial: Nature Publishing Group
Año de publicación: 2021
Nº de páginas: 10
Tipo de publicación: Artículo de Revista
DOI: 10.1038/s41598-021-89236-x
ISSN: 2045-2322
Url de la publicación: https://www.doi.org/10.1038/s41598-021-89236-x
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IRUZUBIETA, PAULA
FERNÁNDEZ-LANAS, TATIANA
RASINES, LAURA
CAYON, LORENA
ÁLVAREZ-CANCELO, ANA
SANTOS-LASO, ALVARO
GARCÍA-BLANCO, AGUSTÍN
CURIEL-OLMO, SORAYA
CABEZAS, JOAQUÍN
WALLMANN, REINHARD
EMILIO FABREGA GARCIA
VICTOR MANUEL MARTINEZ TABOADA
JOSE LUIS HERNANDEZ HERNANDEZ
MARCOS LOPEZ HOYOS
LAZARUS, JEFFREY V
JAVIER CRESPO GARCIA
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