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Detalle_Publicacion

Gold nanodoughnut as an outstanding nanoheater for photothermal applications

Abstract: Photoinduced hyperthermia is a cancer therapy technique that induces death to cancerous cells via heat generated by plasmonic nanoparticles. While previous studies have shown that some nanoparticles can be effective at killing cancer cells under certain conditions, there is still a necessity (or the need) to improve its heating efficiency. In this work, we perform a detailed theoretical study comparing the thermoplasmonic response of the most effective nanoparticle geometries up to now with a doughnut-shaped nanoparticle. We numerically demonstrate that the latter exhibits a superior tunable photothermal response in practical illumination conditions (unpolarized light). Furthermore, we show that nanoparticle heating in fluidic environments, i.e., nanoparticles undergoing Brownian rotations, strongly depends on the particle orientation with respect to the illumination source. We conclude that nanodoughnuts are the best nanoheaters in our set of structures, with an average temperature increment 40% higher than the second best nanoheater (nanodisk). Furthermore, nanodoughnuts feature a weak dependence on orientation, being therefore ideal candidates for photothermal therapy applications. Finally, we present a designing guide, covering a wide range of toroid designs, which can help on its experimental implementation.

Otras publicaciones de la misma revista o congreso con autores/as de la Universidad de Cantabria

 Fuente: Optics Express, 2022, 30 (1), 125 - 137

Editorial: The Optical Society (OSA)

 Fecha de publicación: 01/01/2022

Nº de páginas: 13

Tipo de publicación: Artículo de Revista

 DOI: 10.1364/OE.446637

ISSN: 1094-4087

 Proyecto español: PGC2018-096649-B-I

Url de la publicación: https://doi.org/10.1364/OE.446637