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Biomarker responsiveness in different tissues of caged Ruditapes philippinarum and its use within an integrated sediment quality assessment

Abstract: Biomarkers comprising activities of biotransformation enzymes (ethoxyresorufin-O-deethylase-EROD-, dibenzylfluorescein dealkylase -DBF-, glutathione S-transferase-GST), antioxidant enzymes (glutathione reductase -GR- and glutathione peroxidase -GPX), lipid peroxidation -LPO- and DNA strand breaks were analyzed in the clam Ruditapes philippinarum caged at Cádiz Bay, Santander Bay and Las Palmas de Gran Canaria (LPGC) Port (Spain). Sediments were characterized. Digestive gland was the most sensitive tissue to sediment contamination. In Cádiz Bay, changes in LPO regarding day 0 were related with metals. In LPGC Port, DBF, EROD, and GST activity responses suggested the presence of undetermined contaminants which might have led to DNA damage. In Santander Bay, PAHs were related with EROD activity, organic and metal contamination was found to be associated with GR and GST activities and DNA damage presented significant (p < 0.05) induction. R. philippinarum was sensitive to sediment contamination at biochemical level. Biomarkers allowed chemical exposure and sediment quality assessment.

Otras publicaciones de la misma revista o congreso con autores/as de la Universidad de Cantabria

 Autoría: Ramos-Gómez J., Coz A., Viguri J., Luque A., Martín-Díaz M., DelValls T.,

 Fuente: Environmental Pollution, 2011, 159(7), 1914-1922

Editorial: Elsevier

 Fecha de publicación: 01/07/2011

Nº de páginas: 9

Tipo de publicación: Artículo de Revista

 DOI: 10.1016/j.envpol.2011.03.030

ISSN: 0269-7491,1873-6424

 Proyecto español: CTM2008-06344-C03-02

Url de la publicación: https://doi.org/10.1016/j.envpol.2011.03.030

Autoría

RAMOS-GÓMEZ, JULIA

MARIA LAURA MARTIN DIAZ

ANGEL DEL VALLS CASILLAS