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External validation of the risk quantification of early outcome after lung transplantation scale

Abstract: Objective To validate the ?Risk Quantification of Early Outcome After Lung Transplantation? (RQLT) scale in a cohort of lung transplantation patients. Design The parameters included in the RQLT scale were recorded prospectively. Patient A total of 74 lung transplant patients in the University Hospital Marquis of Valdecilla (Santander) were analyzed between September 2004 and March 2008. Main variables of interest This was the association of the score on the RQLT scale with mortality at 30 days and prolonged ICU stay. The dependent variable of mortality at 30 days was adjustment of scale using the logistic regression model. Diagnostic efficacy was evaluated using the ROC curve and calibration of the system on the sample with the Hosmer and Lemeshow goodness of fit test. Results The 30-day mortality in lung transplant patients increases significantly as the RQLT score increases, with an odds ratio (OR) of 2.20 (1.24?3.93) for each point increase on the RQLT scale. The area under the ROC curve for 30-day mortality was 0.79 (0.68?0.88; P=0.01). The Hosmer and Lemeshow goodness of fit test described a value p=0.58. Conclusions The RQLT scale is a useful tool as an indicator of 30-day mortality in transplant patients.

 Autoría: González-Castro A., Díaz-Regañón G., Fernández-Miret B., Suberviola-Cañas B., Llorca J., Miñambres E.,

 Fuente: Medicina Intensiva, 2010, 34(7), 446-452

 Editorial: Ediciones Doyma, S.L.

 Fecha de publicación: 01/10/2010

 Nº de páginas: 7

 Tipo de publicación: Artículo de Revista

 DOI: 10.1016/j.medin.2010.02.003

 ISSN: 0210-5691,1578-6749

 Url de la publicación: https://doi.org/10.1016/j.medin.2010.02.003

Autoría

ALEJANDRO GONZALEZ CASTRO

DÍAZ-REGAÑÓN, G.

FERNÁNDEZ-MIRET, B.

BORJA SUBERVIOLA CAÑAS

FRANCISCO JAVIER LLORCA DIAZ