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Applicability of the 2006 European League Against Rheumatism (EULAR) criteria for the classification of Henoch-Schönlein purpura. An analysis based on 766 patients with cutaneous vasculitis

Abstract: Objectives: In 2006 the European League Against Rheumatism (EULAR) proposed new classification criteria for Henoch-Schönlein purpura (HSP). We aimed to establish the applicability of these criteria in patients with primary cutaneous vasculitis (CV). We also compared these criteria with previously established classification criteria for HSP. Methods: A series of 766 (346 women/420 men; mean age 34 years) consecutive unselected patients with CV was assessed. One hundred and twenty-four of them with secondary CV or with CV associated with other well defined entities were excluded from the analysis. The 2006 EULAR criteria for HSP were tested in the remaining 642 patients with primary CV. Two sets of criteria for HSP were used for comparisons: a) the 1990 American College of Rheumatology (ACR-1990), and b) the ACR modified criteria proposed by Michel et al. in 1992 (Michel-1992). Results: 451 (70.2%) of 642 patients were classified as having HSP according to the EULAR-2006 criteria, 405 (63.1%) using the ACR-1990 criteria, and 392 (61.1%) by the Michel-1992 criteria. However, only 336 patients (52.3%) met at the same time the EULAR-2006 and the ACR-1990 criteria, and only 229 patients (35.7%) fulfilled both the EULAR-2006 and Michel-1992 criteria. It is noteworthy that only 276 (43%) patients met the three set of criteria. Children fulfilled all the sets of criteria more commonly than adults (215 [66.6%] of 323 vs. 61 [19%] of 319, respectively; p<0.0001). Conclusions: According to our results, the EULAR-2006 criteria show low concordance with previous sets of classification criteria used for HSP.

 Fuente: Clinical and Experimental Rheumatology, 2015, 33(S89), S44-S47

 Publisher: Clinical and Experimental Rheumatology

 Year of publication: 2015

 No. of pages: 4

 Publication type: Artículo de Revista

 ISSN: 0392-856X,1593-098X

 Spanish project: RD08/0075 (RIER) ; RD12/0009/0013

Authorship

ORTIZ SANJUÁN, FRANCISCO

LORICERA, JAVIER

LACALLE CALDERÓN, MARINA

PINA MURCIA, TRINITARIO

CALVO RÍO, VANESA

JESUS LINO ALVAREZ GRANDA