Abstract: Background: Some studies have suggested an association between migraine and inflammatory bowel disease. We determined migraine prevalence in a cohort of patients with inflammatory bowel disease. Methods: Patients with inflammatory bowel disease aged 18?65 years were interviewed using an ad hoc headache questionnaire. Those who admitted a history of headache in the last year answered the three questions of the ID-Migraine questionnaire. Those who answered "yes" to the three of them were classified as "definite" and those who answered "yes" to two were classified as "probable" migraine. Results: We interviewed 283 patients with inflammatory bowel disease. Of these, 176 (62.2%) had headache. Fifty-nine (20.8%; 95% CI 16.3?26.0%) met migraine criteria either definite (n?=?33; 11.7%; 95% CI 8.2?16.0%) or probable (n?=?26; 9.2%; 95% CI 6.1?13.2). When divided by gender, 12 men (9.6%; 95% CI 5.1?16.2%) and 47 women (29.8%; 95% CI 22.8?37.5%) met migraine criteria. The prevalence of migraine was increased in inflammatory bowel disease patients from the current cohort (20.8%) versus that reported for our general population for the same age group (12.6%; p?

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