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Subacute encephalopathy with seizures in alcoholics (SESA syndrome) revisited

Abstract: Purpose: The aim of this paper is to describe two additional cases of subacute encephalopathy with seizures in alcoholics (SESA syndrome), and to propose that this entity now should be considered as a subtype of nonconvulsive status epilepticus (NCSE). Methods: We retrospectively analyzed the clinical characteristics, electroencephalography (EEG), neuroimaging data, and prognosis of these two further cases of SESA syndrome. In addition, we compare our findings with the cases previously described in the English literature in order to propose new diagnostic criteria. Results: Two adults with history of chronic alcohol abuse were admitted because of confusion and seizures. A routine EEG showed frequent periodic lateralized epileptiform discharges (PLEDs) localized over the right temporal regions. In one case, we captured two complex partial seizures (CPSs) arising from the right hemisphere. Neuroimaging studies revealed subjacent chronic vascular pathology. Following transfer to the intensive care unit (ICU), both improved to antiepileptic treatment and were discharged with full recovery. Conclusion: On the basis of our findings and a review of the literature, we suggest that SESA syndrome represents a subtype of partial or localization-related NCSE given its particular clinical, electroencephalographic, neuroimaging and prognostic characteristics.

 Autoría: Fernández-Torre J., Kaplan P.,

 Fuente: Seizure - European journal of epilepsy, 2014, 23(5), 393-396

 Editorial: Elsevier

 Año de publicación: 2014

 Nº de páginas: 4

 Tipo de publicación: Artículo de Revista

 DOI: 10.1016/j.seizure.2014.02.002

 ISSN: 1059-1311,1532-2688

 Url de la publicación: https://doi.org/10.1016/j.seizure.2014.02.002