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Abstract: Tau is a microtubule-associated protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. In this review, we focus on the primary, secondary, tertiary, and quaternary tau structures. We describe the structure of tau from its specific residues until its conformation in dimers, oligomers, and larger polymers in physiological and pathological situations.
Fuente: Front. Aging Neurosci., 08 November 2016 Volume 8 Article 262
Editorial: Frontiers Research Foundation
Fecha de publicación: 01/11/2016
Nº de páginas: 10
Tipo de publicación: Artículo de Revista
DOI: 10.3389/fnagi.2016.00262
ISSN: 1663-4365
Consultar en UCrea Leer publicación
ÁVILA, JESÚS
JIMÉNEZ, JUAN S.
SAYAS, CARMEN L.
BOLÓS, MARTA
JUAN CARLOS ZABALA OTAÑO
RIVAS, GERMÁN
HERNÁNDEZ, FÉLIX
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