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18F-sodium fluoride PET/CT for the in vivo visualization of Mönckeberg's sclerosis in a diabetic patient

Abstract: Diabetes is a major frequent cause of atherosclerosis vascular disease. Arterial calcification in diabetic patients is responsible for peripheral vascular involvement. Molecular imaging using 18F-sodium fluoride (18F-NaF) positron emission tomography (PET)/computed tomography (CT) has been recently proposed as a marker to study the in vivo mineralization process in the atheroma plaque. A 69-year-old man with a history of type 2 diabetes and no clinical evidence of peripheral arterial disease underwent an 18F-NaF PET/CT scan. A linear, well-defined 18F-NaF uptake was detected along the femoral arteries. In addition, the CT component of the PET/CT identified an unsuspected ?tram-track? calcification in his femoral arteries, suggestive of medial calcification (Mönckeberg?s sclerosis). In other vascular territories, focal 18F-NaF uptake was also detected in carotid and aorta atheroma plaques. Molecular imaging with 18F-NaF PET/CT might provide new functional information about the in vivo vascular calcification process in diabetic patients.

 Fuente: Revista Española de Medicina Nuclear e Imagen Molecular, 2015 34(5), 314-316

 Editorial: Elsevier

 Año de publicación: 2015

 Nº de páginas: 3

 Tipo de publicación: Artículo de Revista

 DOI: 10.1016/j.remn.2015.04.004

 ISSN: 2253-654X,2253-8070,2253-8089

 Url de la publicación: https://doi.org/10.1016/j.remn.2015.04.004

Autoría

Mª ISABEL MARTINEZ RODRIGUEZ

BANZO, I.

ARCOCHA TORRES, M. DE

JULIO FRANCISCO JIMENEZ BONILLA

MARTÍNEZ AMADOR, N.

IBÁÑEZ BRAVO, S.

RAMOS, L.

JOSE ANTONIO AMADO SEÑARIS

JOSE MANUEL CARRIL CARRIL