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Expanding the Donor Pool Through Intensive Care to Facilitate Organ Donation: Results of a Spanish Multicenter Study

Abstract: BACKGROUND: Intensive Care to facilitate Organ Donation (ICOD) may help to increase the donor pool. We describe the Spanish experience with ICOD. METHODS: Achieving Comprehensive Coordination in Organ Donation (ACCORD)-Spain consisted of an audit of the donation pathway from patients who died as a result of a devastating brain injury (possible donors) in 68 hospitals during November 1, 2014, to April 30, 2015. We focused on possible donors whose families were interviewed to discuss organ donation once intensive care with a therapeutic purpose was deemed futile and brain death (BD) was a likely outcome. RESULTS: Of the 1970 possible donors in ACCORD-Spain, in 257, the family was interviewed once the decision had been made not to intubate/ventilate (n = 105), with the patient under intubation/ventilation outside of the intensive care unit (n = 59), or with the patient intubated/ventilated within the intensive care unit (n = 93).Consent to ICOD was obtained in 174 cases. Consent was higher when the donor coordinator participated in the interview (odds ratio, 2.32; 95% confidence interval, 1.33-4.11; P = 0.003). One hundred thirty-one patients developed BD, of whom 117 transitioned to actual donation after BD. Of the 35 patients who did not develop BD, 2 transitioned to actual donation after circulatory death. Sixteen patients subject to ICOD were finally medically unsuitable organ donors.ICOD contributed to 24% of the 491 actual donors registered in ACCORD-Spain. CONCLUSIONS: Despite the complexity of the interview, the majority of families consented to ICOD. Estimating the probability of BD and assessing medical suitability are additional challenges of the practice. ICOD represents a clear opportunity to increase the donor pool and ensures organ donation is posed at every end-of-life care pathway.

Otras publicaciones de la misma revista o congreso con autores/as de la Universidad de Cantabria

 Fuente: Transplantation. 2017 Aug;101(8):e265-e272

Editorial: Lippincott Williams & Wilkins

 Año de publicación: 2017

Nº de páginas: 8

Tipo de publicación: Artículo de Revista

 DOI: 10.1097/TP.0000000000001701

ISSN: 0041-1337,1534-6080

Url de la publicación: https://www.doi.org/10.1097/TP.0000000000001701

Autoría

DOMÍNGUEZ-GIL, BEATRIZ

COLL, ELISABETH

ELIZALDE, JOSÉ

HERRERO, JAIME E.

PONT, TERESA

QUINDÓS, BRÍGIDA

MARCELO, BELLA

BODÍ, MARÍA A.

MARTÍNEZ, ADOLFO

NEBRA, AGUSTÍN

GUERRERO, FRANCISCO

MANCIÑO, JOSÉ M.

GALÁN, JUAN

LEBRÓN, MIGUEL

MATESANZ, RAFAEL

ACCORD-SPAIN STUDY GROUP