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2015 Recommendations for the Management of Polymyalgia Rheumatica: a European League Against Rheumatism/American College of Rheumatology Collaborative Initiative

Abstract: Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients? and clinicians? values and preferences, and resource use. Eight overarching principles and nine specific recommendations were developed covering several aspects of PMR, including basic and follow-up investigations of patients under treatment, risk factor assessment, medical access for patients and specialist referral, treatment strategies such as initial glucocorticoid (GC) doses and subsequent tapering regimens, use of intramuscular GCs and disease modifying anti-rheumatic drugs (DMARDs), as well as the roles of non-steroidal anti-rheumatic drugs and non-pharmacological interventions. These recommendations will inform primary, secondary and tertiary care physicians about an international consensus on the management of PMR. These recommendations should serve to inform clinicians about best practices in the care of patients with PMR.

 Authorship: Dejaco C., Singh Y.P., Perel P., Hutchings A., Camellino D., Mackie S., Abril A., Bachta A., Balint P., Barraclough K., Bianconi L., Buttgereit F., Carsons S., Ching D., Cid M., Cimmino M., Diamantopoulos A., Docken W., Duftner C., Fashanu B., Gilbert K., Hildreth P., Hollywood J., Jayne D., Lima M., Maharaj A., Mallen C., Martinez-Taboada V., Maz M., Merry S., Miller J., Mori S., Neill L., Nordborg E., Nott J., Padbury H.,

 Fuente: Arthritis and Rheumatology, 2015, 67(19), 2569-2580

 Publisher: John Wiley and Sons Ltd

 Year of publication: 2015

 Publication type: Article

 DOI: 10.1002/art.39333

 ISSN: 2326-5205,2326-5191

 Publication Url: https://doi.org/10.1002/art.39333

Authorship

DEJACO, CHRISTIAN

SINGH, YOGESH P.

PEREL, PABLO

HUTCHINGS, ANDREW

CAMELLINO, DARIO

MACKIE, SARAH

ABRIL, ANDY

BACHTA, ARTUR

BALINT, PETER

BARRACLOUGH, KEVIN

BIANCONI, LINA

BUTTGEREIT, FRANK

CARSONS, STEVEN

CHING, DANIEL

CID, MARIA

CIMMINO, MARCO

DIAMANTOPOULOS, ANDREAS

DOCKEN, WILLIAM

DUFTNER, CHRISTINA