Abstract: Cancer is a very common cause of death with more than 10 million cases worldwide. New strategies are needed to improve the existing treatments. Magnetic hyperthermia based on the use of magnetic nanoparticles (MNPs) is a step forward and object of overwhelming number of studies. Most of suitable MNPs contain cores of magnetite/maghemite harmless to human beings. Recently a new family of MNPs forming nanoflowers were produced with a relevant performance. These are multicore MNPs grouped closely. The origin of the performance is not obvious as a combination of sizes, magnetic anisotropy, interactions among cores and interations among MNPS are combined. With SANS experiments (POLARIS) it is possible the evaluation of supermagnetic and inner order of MNPS ensembles of nanoflowers. We aim to disclose the modification in the supermagnetic and intra magnetic coupling by using a set of nanoflowers with different sizes of the core (10 - 30 nm) and of the nanoflower (30-280 nm) in powder and D2O solutions.

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