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Abstract: Most children and adolescents infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain asymptomatic or develop a mild coronavirus disease 2019 (COVID-19) that usually does not require medical intervention. However, a small proportion of pediatric patients develop a severe clinical condition, multisystem inflammatory syndrome in children (MIS-C). The involvement of epigenetics in the control of the immune response and viral activity prompted us to carry out an epigenomic study to uncover target loci regulated by DNA methylation that could be altered upon the appearance of MIS-C.
Fuente: www.thelancet.com Vol 50 Month , 2022
Publisher: Elsevier
Year of publication: 2022
No. of pages: 12
Publication type: Article
DOI: 10.1016/j.eclinm.2022.101515
ISSN: 0140-6736,1474-547X
Publication Url: https://doi.org/10.1016/j.eclinm.2022.101515
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DÁVALOS, VERÓNICA
GARCÍA-PRIETO, CARLOS A.
FERRER, GERARDO
AGUILERA-ALBESA, SERGIO
VALENCIA-RAMOS, JUAN
RODRÍGUEZ-PALMERO, AGUSTÍ
RUIZ, MONTSERRAT
PLANAS-SERRA, LAURA
JORDÁN, IOLANDA
ALEGRÍA, IOSUNE
FLORES-PÉREZ, PATRICIA
CANTARÍN, VERÓNICA
FUMADÓ, VERÓNICA
MARIA TERESA VIADERO UBIERNA
RODRIGO, CARLOS
MÉNDEZ-HERNÁNDEZ, MARÍA
LÓPEZ-GRANADOS, EDUARDO
COLOBRAN, ROGER
RIVIÈRE, JACQUES G.
SOLER-PALACÍN, PERE
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