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Abstract: Plasmids are universally present in bacteria and play key roles in the dissemination of genes such as antibiotic resistance determinants. Major concepts in Plasmid Biology derive from the efforts to classify plasmids. Here, we review the main plasmid classification systems, starting by phenotype-based methods, such as fertility inhibition and incompatibility, followed by schemes based on a single gene (replicon type and MOB class), and finishing with recently developed approaches that use genetic distances between whole plasmid sequences. A comparison of the latter highlights significant differences between them. We further discuss the need for an operational definition of plasmid species that reveals their biological features, akin to plasmid taxonomic units (PTUs)
Fuente: Plasmid, 2023, 126, 102684
Publisher: Academic Press Inc.
Year of publication: 2023
No. of pages: 10
Publication type: Article
DOI: 10.1016/j.plasmid.2023.102684
ISSN: 0147-619X,1095-9890
Spanish project: PID2020-117923GB-I00
Publication Url: https://doi.org/10.1016/j.plasmid.2023.102684
Consult in UCrea Read publication
MARIA PILAR GARCILLAN BARCIA
SANTIAGO REDONDO SALVO
FERNANDO DE LA CRUZ CALAHORRA
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