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Abstract: Different techniques have proven to be useful in determining the presence of subclinical cardiovascular disease in patients with rheumatoid arthritis (RA). Doppler imaging with iontophoresis of acetylcholine and flow-mediated, endothelium-dependent vasodilation give information on endothelial dysfunction, an early step in the atherogenesis process. However, there is no good correlation between these two surrogate markers of cardiovascular disease in RA. A single determination of routine laboratory markers of inflammation does not seem to relate to endothelial function in RA. Further research is needed to determine whether microvascular endothelial function is a better predictor of cardiovascular outcome than macrovascular endothelial function in patients with RA.
Fuente: Arthritis Research & Therapy, 2012, 14,122
Publisher: BioMed Central
Year of publication: 2012
No. of pages: 2
Publication type: Article
DOI: 10.1186/ar3891
ISSN: 1478-6354,1478-6362
Publication Url: https://doi.org/10.1186/ar3891
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MIGUEL ANGEL GONZALEZ-GAY MANTECON
CARLOS GONZALEZ JUANATEY
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