Abstract: This paper contains some proposals for sampling oriented to the weekly estimation of the real proportion of individuals that have been infected (present or past infection) by SARS-COV-2. During the months of May to July 2020, Instituto de Salud Carlos III in collaboration with the Instituto Nacional de Estadística carried out three monthly surveys to estimate the number of people with virus antibodies in each province. Complementing the results of these surveys, increasing their periodicity to weeks, would be of great help for health decision-making.

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