Buscar

Estamos realizando la búsqueda. Por favor, espere...

Increasing incidence of mucormycosis in spanish inpatients from 1997 to 2018

Abstract: Background Mucormycosis is a worldwide angio-invasive fungal infection that is associated with high morbidity and mortality. A few European studies have focused on the epidemiology. Methodology A retrospective longitudinal descriptive study was performed with inpatients diagnosed with mucormycosis (ICD-9-CM, code 117.7, cases 1997-2015; and ICD-10, code B46, cases 2016-2018; along with length of hospital stay) in Spanish public hospitals between 1 January 1997 and 31 December 2018. Data were obtained from the Minimum Basic Data Set (CMBD in Spanish). Principal findings A total of 962 patients were recorded; 665 were men. The mean age (±SD) was 55 ± 18.8 years. The annual incidence rate increased from 0.74 to 1.24 cases per million person-years. The lethality rate was 31.3%. Renal failure (41.6%) and haematological malignancy (36.3%) were the main factors involved. Conclusions Mucormycosis is a rare infectious disease in Spain, but it has had a significantly increased incidence in the last two decades. Being an adult male and having diabetes, neoplasm or renal failure are the main factors associated. High mortality is usually associated mainly with haematological malignancy and renal failure. CMBD studies could be an efficient tool for assessing changes in the epidemiology of mucormycosis.

 Fuente: Mycoses, 2022, 65, 344-353

 Editorial: Wiley-Blackwell

 Fecha de publicación: 01/03/2022

 Nº de páginas: 10

 Tipo de publicación: Artículo de Revista

 DOI: 10.1111/myc.13418

 ISSN: 0933-7407,1439-0507

 Url de la publicación: https://doi.org/10.1111/myc.13418

Autoría

PARRA FARIÑAS, RAÚL

ALONSO-SARDÓN, MONTSERRAT

VELASCO TIRADO, VIRGINIA

GALINDO PÉREZ, INMACULADA

CARBONELL, CRISTINA

ÁLVAREZ ARTERO, ELISA

ROMERO-ALEGRÍA, ÁNGELA

BELHASSEN-GARCÍA, MONCEF