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Consumption of aspartame and other artificial sweeteners and risk of cancer in the Spanish multicase-control study (MCC-Spain)

Abstract: Use of artificial sweeteners (AS) such as aspartame, cyclamate, saccharin and sucralose is widespread. We evaluated the association of use of aspartame and other AS with cancer. In total 1881 colorectal, 1510 breast, 972 prostate and 351 stomach cancer and 109 chronic lymphocytic leukaemia (CLL) cases and 3629 population controls from the Spanish Multicase-Control (MCC-Spain) study were recruited (2008-2013). The consumption of AS, from table-top sweeteners and artificially sweetened beverages, was assessed through a self-administered and validated food frequency questionnaire (FFQ). Sex-specific quartiles among controls were determined to compare moderate consumers (

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Autoría: Palomar-Cros A., Straif K., Romaguera D., Aragonés N., Castaño-Vinyals G., Martin V., Moreno V., Gómez-Acebo I., Guevara M., Aizpurua A., Molina-Barceló A., Jiménez-Moleón J.J., Tardón A., Contreras-Llanes M., Marcos-Gragera R., Huerta J.M., Pérez-Gómez B., Espinosa A., Hernández-Segura N., Obón-Santacana M., Alonso-Molero J., Burgui R., Amiano P., Pinto-Carbó M., Olmedo-Requena R., Fernández-Tardón G., Santos-Sánchez V., Fernández de Larrea-

Fuente: International Journal of Cancer, 2023, 153, 979-993

Editorial: Wiley-Liss

Año de publicación: 2023

Nº de páginas: 16

Tipo de publicación: Artículo de Revista

DOI: 10.1002/ijc.34577

ISSN: 0020-7136,1097-0215

Proyecto español: RD12/0036/0036

Url de la publicación: https://doi.org/10.1002/ijc.34577

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