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In vitro activities of retapamulin and 16 other antimicrobial agents against recently obtained Streptococcus pyogenes isolates

Abstract: Retapamulin in vitro activity against 400 Streptococcus pyogenes clinical isolates obtained from skin, pharynx, ear fluid, and blood samples recovered from 2007 to 2009 was studied. The isolates belonged to 26 different emm types, including isolates nonsusceptible to erythromycin (n = 187), tetracycline (n = 99), ciprofloxacin (n = 59), and bacitracin (n = 43). Results were compared to the activities of 16 other antibiotics for topical and systemic use. Retapamulin MICs ranged from ?0.015 to 0.12 ?g/ml, showing the highest intrinsic activity among the topical antimicrobial drugs studied.

 Fuente: Antimicrobial Agents and Chemotherapy, 2011, 55(5), 2406-2408

 Editorial: American Society for Microbiology

 Año de publicación: 2011

 Nº de páginas: 3

 Tipo de publicación: Artículo de Revista

 DOI: 10.1128/AAC.01665-10

 ISSN: 0066-4804,1098-6596,1070-6283

 Proyecto español: PI 08/0808

Autoría

PÉREZ-TRALLERO, EMILIO

MONTES, MILAGROSA

GARCÍA-ARENZANA, JOSÉ M.

IRIARTE, VICTOR