Abstract: In the current Research Topic (RT), we provide insights on the small GTPase biology, from protein
synthesis to disease, by presenting a Research Topic of original and review articles describing distinct
GTPases, with special attention to RAS proteins. The RAS superfamily comprises a large family of small
GTPases, where the members of the RAS, RHO, and RAB families are the most well-characterized. These
small proteins cycle between a GDP-bound inactive and a GTP-bound active state, thus mediating several
cellular processes such as intracellular trafficking, cytoskeletal organization, cell migration, proliferation,
differentiation, and gene expression.
Other publications of the same journal or congress with authors from the University of Cantabria
