Lysosomes, caspase-mediated apoptosis, and cytoplasmic activation of P21, but not cell senescence, participate in a redundant fashion in embryonic morphogenetic cell death

Article

Cell Death and Disease, 2023, 14, 813

 Authorship: CRISTINA DUARTE OLIVENZA, GORETTI MORÁN DE LUIS, JUAN MARIO HURLE GONZALEZ, CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO MONTERO SIMON

 2023

Transforming growth factor beta signaling: The master sculptor of fingers

Article

Developmental Dynamics, 2022, 251(1), 125-136

 Authorship: CARLOS IGNACIO LORDA DIEZ, CRISTINA DUARTE OLIVENZA, JUAN MARIO HURLE GONZALEZ, JUAN ANTONIO MONTERO SIMON

 2022

Modeling the Differentiation of Embryonic Limb Chondroprogenitors by Cell Death and Cell Senescence in High Density Micromass Cultures and Their Regulation by FGF Signaling

Article

Cells, 2022, 12(1), 175

 Authorship: CRISTINA DUARTE OLIVENZA, JUAN MARIO HURLE GONZALEZ, JUAN ANTONIO MONTERO SIMON, CARLOS IGNACIO LORDA DIEZ

 2022

Regulation of developmental cell death in the animal kingdom: a critical analysis of epigenetic versus genetic factors

Article

International Journal of Molecular Sciences 2022, 23, 1154

 Authorship: JUAN ANTONIO MONTERO SIMON, CARLOS IGNACIO LORDA DIEZ, JUAN MARIO HURLE GONZALEZ

 2022

Histone epigenetic signatures in embryonic limb interdigital cells fated to die

Article

Cells , 2021, 10(4), 911

 Authorship: CRISTINA SANCHEZ FERNANDEZ, CARLOS IGNACIO LORDA DIEZ, CRISTINA DUARTE OLIVENZA, JUAN MARIO HURLE GONZALEZ, JUAN ANTONIO MONTERO SIMON

 2021

Effects of berberine on the chondrogenic differentiation of embryonic limb skeletal progenitors

Article

Journal of Inflammation Research, 2021, 29(14), 5001-5011

 Authorship: CRISTINA DUARTE OLIVENZA, JUAN ANTONIO MONTERO SIMON, CARLOS IGNACIO LORDA DIEZ

 2021

Cell death in the developing vertebrate limb: a locally regulated mechanism contributing to musculoskeletal tissue morphogenesis and differentiation

Article

Developmental Dynamics, 2021, 250(9), 1236-1247

 Authorship: JUAN ANTONIO MONTERO SIMON, CARLOS IGNACIO LORDA DIEZ, CRISTINA SANCHEZ FERNANDEZ, JUAN MARIO HURLE GONZALEZ

 2021

The methylation status of the embryonic limb skeletal progenitors determines their cell fate in chicken

Article

Communications Biology, 2020, 3(1), 283

 Authorship: CRISTINA SANCHEZ FERNANDEZ, CARLOS IGNACIO LORDA DIEZ, JUAN MARIO HURLE GONZALEZ, JUAN ANTONIO MONTERO SIMON

 2020

Confluence of cellular degradation pathways during interdigital tissue remodeling in embryonic tetrapods

Article

Frontiers in Cell and Developmental Biology, 2020, 23(8), 593761

 Authorship: JUAN ANTONIO MONTERO SIMON, CARLOS IGNACIO LORDA DIEZ, JUAN MARIO HURLE GONZALEZ

 2020

Cell senescence, apoptosis and DNA damage cooperate in the remodeling processes accounting for heart morphogenesis

Article

Journal of Anatomy, 2019, 234, 815--829

 Authorship: CARLOS IGNACIO LORDA DIEZ, MICHELLE E. SOLIS-MANCILLA, CRISTINA SANCHEZ FERNANDEZ, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ, JUAN ANTONIO MONTERO SIMON

 2019

UHRF genes regulate programmed interdigital tissue regression and chondrogenesis in the embryonic limb

Article

Cell Death and Disease, 2019, 10(5), 347

 Authorship: CRISTINA SANCHEZ FERNANDEZ, CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN ANTONIO MONTERO SIMON, JUAN MARIO HURLE GONZALEZ

 2019

Four and a half domain 2 (FHL2) scaffolding protein is a marker of connective tissues of developing digits and regulates fibrogenic differentiation of limb mesodermal progenitors

Article

Journal of Ttissue Engineering and Regenerative Medicine, 2018, 12(4), 1-11

 Authorship: CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO MONTERO SIMON, CRISTINA SANCHEZ FERNANDEZ, JUAN ANTONIO GARCIA-PORRERO PEREZ, J. CHIMAL MONROY, JUAN MARIO HURLE GONZALEZ

 2018

Sox9 expression in amniotes: species-specific differences in the formation of digits

Article

Frontiers in Cell and Developmental Biology, 2017, 5, 23

 Authorship: JUAN ANTONIO MONTERO SIMON, CARLOS IGNACIO LORDA DIEZ, JAVIER FRANCISCO MORCILLO, JESÚS CHIMAL MONROY, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ

 2017

Interdigital tissue remodelling in the embryonic limb involves dynamic regulation of the miRNA profiles

Article

Journal of Anatomy, 2017, 231, 275-286

 Authorship: BEATRIZ GARCIA RIART, CARLOS IGNACIO LORDA DIEZ, JESSICA C. MARIN LLERA, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ, JUAN ANTONIO MONTERO SIMON

 2017

DNA damage precedes apoptosis during the regression of the interdigital tissue in vertebrate embryos

Article

Scientific Reports, 2016, 6, 35478

 Authorship: JUAN ANTONIO MONTERO SIMON, CRISTINA SANCHEZ FERNANDEZ, CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ

 2016

The tumor suppressor BTG1 is expressed in the developing digits and regulates skeletogenic differentiation of limb mesodermal progenitors in high density cultures

Article

Cell and Tissue Research, 2016, 364, 299-308

 Authorship: CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO MONTERO SIMON, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ

 2016

Apoptosis during embryonic tissue remodeling is accompanied by cell senescence

Article

Aging, 2015, 7(11), 974-985

 Authorship: CARLOS IGNACIO LORDA DIEZ, BEATRIZ INMACULADA GARCIA RIART MONZON, JUAN ANTONIO MONTERO SIMON, J RODRÍGUEZ LEÓN, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ

 2015

Interdigital tissue regression in the developing limb of vertebrates

Article

The International Journal of Developmental Biology, 2015, 59, 55-62

 Authorship: CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO MONTERO SIMON, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ

 2015

Divergent differentiation of skeletal progenitors into cartilage and tendon: lessons from the embryonic limb

Article

ACS Chemical Biology, 2014, 9(1), 72-79

 Authorship: CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO MONTERO SIMON, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ

 2014

Reelin/DAB-1 signaling in the embryonic limb regulates the chondrogenic differentiation of digit mesodermal progenitors

Article

Journal of Cellular Physiology, 2014, 229(10), 1397-1404

 Authorship: MANUEL JESUS DIAZ MENDOZA, CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO MONTERO SIMON, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ

 2014

Divergent differentiation of skeletal progenitors into cartilage and tendon: lessons from the embryonic limb

Article

ACS Chemical Biology, 2014, 17(9,1), 72-9

 Authorship: CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO MONTERO SIMON, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ

 2014

Decorin gene expression in the differentiation of the skeletal connective tissues of the developing limb

Article

Gene Expression Patterns : GEP, 2014, 15(1), 52-60

 Authorship: CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ, JUAN ANTONIO MONTERO SIMON

 2014

Ligand- and stage-dependent divergent functions of BMP signaling in the differentiation of embryonic skeletogenic progenitors in vitro

Article

J Bone Miner Res. 2014 Mar;29(3):735-48

 Authorship: CARLOS IGNACIO LORDA DIEZ, JUAN ANTONIO MONTERO SIMON, SENYON CHOE, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN MARIO HURLE GONZALEZ

 2014

Comparative transcriptional analysis of three human ligaments with distinct biomechanical properties

Article

Journal of Anatomy, 2013, 223, 593--602

 Authorship: CARLOS IGNACIO LORDA DIEZ, ANA MARIA CANGA VILLEGAS, LUIS CEREZAL, SANTIAGO PLAZA GARCIA, JUAN MARIO HURLE GONZALEZ, JUAN ANTONIO GARCIA-PORRERO PEREZ, JUAN ANTONIO MONTERO SIMON

 2013

CARACTERIZACIÓN DE LAS REDES MOLECULARES RESPONSABLES DE LA SUPERVIVENCIA Y DIVERSIFICACIÓN DE LOS PROGENITORES ESQUELETICOS EMPRIONARIOS HACIA DIFERENTES TEJIDOS CONECTIVOS PrPID2021-125651NB-I00 financiado por MICIU/AEI/10.13039/501100011033/ FEDER, UE

 Apoptosis I

 DEPARTAMENTO DE ANATOMÍA Y BIOLOGÍA CELULAR

Head: JUAN ANTONIO MONTERO SIMON

Typology: Competitive national public projects

Start year: 2022

LA IMPRONTA EPIGENÉTICA DEL DESTINO DE LOS PROGENITORES ESQUELÉTICOS DURANTE LA FORMACIÓN DE LOS DEDOS: MUERTE CELULAR VERSUS CONDROGÉNESIS. Proyecto BFU2017-84046-P financiado por MCIN/ AEI /10.13039/501100011033/ FEDER "Una manera de hacer Europa"

 Apoptosis I

 DEPARTAMENTO DE ANATOMÍA Y BIOLOGÍA CELULAR

Heads: JUAN ANTONIO MONTERO SIMON, JUAN MARIO HURLE GONZALEZ

Typology: Competitive national public projects

Start year: 2018

GENERACIÓN, AMPLIFICACIÓN Y MADURACIÓN ESTRUCTURAL DE TEJIDO TENDINOSO A PARTIR DE PROGENITORES ESQUELÉTICOS

 DEPARTAMENTO DE ANATOMÍA Y BIOLOGÍA CELULAR

Head: CARLOS IGNACIO LORDA DIEZ

Typology: Competitive private projects, competitive autonomic and subcon…

Start year: 2015

MECANISMO Y NUEVA SIGNIFICACIÓN BIOLÓGICA DE LA MUERTE CELULAR INTERDIGITAL RESPONSABLE DE LA SEPARACIÓN DE LOS DEDOS DURANTE EL DESARROLLO DE LAS EXTREMIDADES (BFU2014-54026-P) (MINECO/FEDER,UE)

 Apoptosis I

 DEPARTAMENTO DE ANATOMÍA Y BIOLOGÍA CELULAR

Head: JUAN MARIO HURLE GONZALEZ

Typology: Competitive national public projects

Start year: 2015

ANÁLISIS EXPERIMENTAL Y CARACTERIZACIÓN DEL TRANSCRIPTOMA DE LA CONDROGENESIS DURANTE EL DESARROLLO DE LA EXTREMIDAD (BFU2011-24169)

 Apoptosis I

 DEPARTAMENTO DE ANATOMÍA Y BIOLOGÍA CELULAR

Head: JUAN MARIO HURLE GONZALEZ

Typology: Competitive national public projects

Start year: 2012

PATRÓN Y REGULACIÓN DE LA SENESCENCIA Y MUERTE CELULAR DURANTE LA DIFERENCIACIÓN DE LOS PROGENITORES DE LA EXTREMIDAD EN CULTIVOS TRIDIMENSIONALES

 Authorship: CRISTINA DUARTE OLIVENZA

 Supervision: JUAN ANTONIO MONTERO SIMON , CARLOS IGNACIO LORDA DIEZ 

 Defense date: 14/11/2023