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Abstract: Plasmids are mobile genetic elements found in many clades of Archaea and Bacteria. They drive horizontal gene transfer, impacting ecological and evolutionary processes within microbial communities, and hold substantial importance in human health and biotechnology. To support plasmid research and provide scientists with data of an unprecedented diversity of plasmid sequences, we introduce the IMG/PR database, a new resource encompassing 699 973 plasmid sequences derived from genomes, metagenomes and metatranscriptomes. IMG/PR is the first database to provide data of plasmid that were systematically identified from diverse microbiome samples. IMG/PR plasmids are associated with rich metadata that includes geographical and ecosystem information, host taxonomy, similarity to other plasmids, functional annotation, presence of genes involved in conjugation and antibiotic resistance. The database offers diverse methods for exploring its extensive plasmid collection, enabling users to navigate plasmids through metadata-centric queries, plasmid comparisons and BLAST searches. The web interface for IMG/PR is accessible at https://img.jgi.doe.gov/pr. Plasmid metadata and sequences can be downloaded from https://genome.jgi.doe.gov/portal/IMG_PR.
Fuente: Nucleic Acids Research, 2023, 1-10
Editorial: Oxford University Press
Año de publicación: 2023
Nº de páginas: 13
Tipo de publicación: Artículo de Revista
DOI: 10.1093/nar/gkad964
ISSN: 0305-1048,1362-4962
Consultar en UCrea Leer publicación
CAMARGO, ANTONIO PEDRO
CALL, LEE
ROUX, SIMON
NAYFACH, STEPHEN
HUNTEMANN, MARCEL
PALANIAPPAN, KRISHNAVENI
RATNER, ANNA
CHU, KEN
MUKHERJEEP, SUPRATIM
REDDY, T. B. K.
CHEN, I-MIN A.
IVANOVA, NATALIA N.
ELOE-FADROSH, EMILEY A.
WOYKE, TANJA
BALTRUS, DAVID A.
CASTAÑEDA-BARBA, SALVADOR
FERNANDO DE LA CRUZ CALAHORRA
FUNNELL, BARBARA E.
HALL, JAMES P. J.
MUKHOPADHYAY, AINDRILA
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